ID   A0A251K1R4_MANES        Unreviewed;       591 AA.
AC   A0A251K1R4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN   ORFNames=MANES_10G118700 {ECO:0000313|EMBL:OAY39741.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY39741.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY39741.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY39741.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM004396; OAY39741.1; -; Genomic_DNA.
DR   EMBL; CM004396; OAY39742.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A251K1R4; -.
DR   STRING; 3983.A0A251K1R4; -.
DR   EnsemblPlants; OAY39741; OAY39741; MANES_10G118700.
DR   EnsemblPlants; OAY39742; OAY39742; MANES_10G118700.
DR   Gramene; OAY39741; OAY39741; MANES_10G118700.
DR   Gramene; OAY39742; OAY39742; MANES_10G118700.
DR   OMA; SGVKYMN; -.
DR   OrthoDB; 152619at2759; -.
DR   Proteomes; UP000091857; Chromosome lg10.
DR   CDD; cd05494; Bromodomain_1; 1.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR   InterPro; IPR001487; Bromodomain.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR018359; Bromodomain_CS.
DR   PANTHER; PTHR47809; DNA-BINDING BROMODOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47809:SF2; DNA-BINDING BROMODOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00439; Bromodomain; 1.
DR   PRINTS; PR00503; BROMODOMAIN.
DR   SMART; SM00297; BROMO; 1.
DR   SUPFAM; SSF47370; Bromodomain; 1.
DR   PROSITE; PS00633; BROMODOMAIN_1; 1.
DR   PROSITE; PS50014; BROMODOMAIN_2; 1.
PE   4: Predicted;
KW   Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT   DOMAIN          212..285
FT                   /note="Bromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50014"
FT   REGION          1..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          138..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          308..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..58
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        391..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        417..444
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..463
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..481
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..531
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   591 AA;  65282 MW;  9C6F500CC341A141 CRC64;
     MKRKRGNKKG KQKGPPVPAT TEAVVNLVSL DGEDNSAADE DDDNNNNVDS HNNEEYESGM
     EIDTPSSTGT DQPLNLASIN PDGSIDKTAG KSVGRVKVKL KTSKVLESPS DTDKSSPQLG
     LEKQGVVGDK MEDTGNSLSE IKTGVPGHVS KKPGSIKIKP SKVLGGLNVE KSSTGMAQDE
     SLQQKEPKTP HQEYQYSKQE LDSALLVIKK VMKMDAAEPF NVPVNPEALG IPDYFDIIDT
     PMDFGTICRN LEKGDKYMNS EDVYKDVQYI WDNCYKYNNK GDYILDLMRR VKKNFMKYWT
     AAGLFTEQSR GSSGAEGPQG EDIGASSQGH GKSGQSKQKT KKRHGRRHKL DCLCAICVLK
     RRRREREENA RLAKGQTGGA DNKLAQELKQ EESSLVESPG GEDSSSNMDE SLDPDADAEV
     EGKGQGVKIE DTEQQNSSIK EKHEEAEEDD DDDEEEEDEE VENEIEIKKT GKVETPEFAD
     RSGEEPNQQP GLAGNAGAEG QKHNVKGHAM GQHEEETPKV QHNKDMESQE RRKKAIMFEK
     FHSENPLLLS LCRSLFPDNH KSVWSGPHSL VQREGSARRS SIHAAVETLM K
//