ID   A0A251K8U4_MANES        Unreviewed;       768 AA.
AC   A0A251K8U4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MANES_09G187800 {ECO:0000313|EMBL:OAY42548.1};
OS   Manihot esculenta (Cassava) (Jatropha manihot).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC   Manihot.
OX   NCBI_TaxID=3983 {ECO:0000313|EMBL:OAY42548.1, ECO:0000313|Proteomes:UP000091857};
RN   [1] {ECO:0000313|EMBL:OAY42548.1, ECO:0000313|Proteomes:UP000091857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AM560-2 {ECO:0000313|Proteomes:UP000091857};
RC   TISSUE=Leaf {ECO:0000313|EMBL:OAY42548.1};
RA   Bredeson J.V., Prochnik S.E., Lyons J.B., Schmutz J., Grimwood J.,
RA   Vrebalov J., Bart R.S., Amuge T., Ferguson M.E., Green R., Putnam N.,
RA   Stites J., Rounsley S., Rokhsar D.S.;
RT   "WGS assembly of Manihot esculenta.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM004395; OAY42547.1; -; Genomic_DNA.
DR   EMBL; CM004395; OAY42548.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A251K8U4; -.
DR   EnsemblPlants; OAY42547; OAY42547; MANES_09G187800.
DR   EnsemblPlants; OAY42548; OAY42548; MANES_09G187800.
DR   Gramene; OAY42547; OAY42547; MANES_09G187800.
DR   Gramene; OAY42548; OAY42548; MANES_09G187800.
DR   Proteomes; UP000091857; Chromosome lg9.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   PANTHER; PTHR45660:SF95; HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH4; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091857}.
FT   DOMAIN          558..620
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          623..768
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          80..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..429
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..425
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   768 AA;  86851 MW;  63DFFC9AFEC5FD94 CRC64;
     MGRLSRRSNI STKTSKEQET QRKILQFPVT NKFAQNVQKI KYKEFLLERR VSPRLKAIPK
     DKRPYYGSIR RRKLCASKDD VCSGKTEDDD KRRQFDSPED NAVMNKAKDG GRKNLSDHVS
     KKRSEGVFLE RRVSPRLKNI SADKRPYYGS VQRRKFGSST DYACHKKTEG NEWKKQLDSP
     KDNAGKEKTK ADITFTNTVQ RVPGLNLKQR GSSRLKNTPV DKRLFHVRDD LCGRKNKNDH
     QIILPHYPDG SVSEKKRKAD LLDLASKDGE DRGGKIDFAL GIEPLEHDDT AIMDLKAEAH
     LEHTSSESFP AEGMHQISSA KVMVVSPLML MCKVINNRVQ NSSKQESEKD VFGVNIVQQF
     QKLALLERRV SPRLKGIPKD RRPYYGSTWK GQLNTAKGYV WNNNDPKKQL HSSEDNTKKK
     KTEVNHSMQQ SLSKAAAKDI CDRDAESLLA SGFLPLKCED TEIMGLENGA YVKSMDHKKL
     LLNCIRHKAG AKDCFEQERV SKDSSKLPGL VCEDISYGEE DIPIPVTNMI DPPIAPTGLK
     YTNSIHIATN LSIPSSPSGC NCKGNCTNPK SCSCALLNGS DFPYVRKDGG RLIEPKDVVF
     ECGPRCRCGP KCINRISQRG LKYRLEVYRT LKKGWAVRSW DFIPSGAPVC EYTGILRRSS
     ELDNVSENEF IFQIDCWHTM NGIGGRERRQ GGVSRHARNL MKKLDKAESE SEFCIDGVSC
     GNVTRFINHS CEPNLFVQCI LSSHHDIRLA RIVLFAADDI PPMQCYWS
//