ID A0A251N3W1_PRUPE Unreviewed; 1008 AA.
AC A0A251N3W1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_8G265600 {ECO:0000313|EMBL:ONH94006.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH94006.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH94006.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. KIN-14 subfamily.
CC {ECO:0000256|ARBA:ARBA00010899}.
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DR EMBL; CM007658; ONH94006.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251N3W1; -.
DR STRING; 3760.A0A251N3W1; -.
DR EnsemblPlants; ONH94006; ONH94006; PRUPE_8G265600.
DR Gramene; ONH94006; ONH94006; PRUPE_8G265600.
DR eggNOG; KOG0239; Eukaryota.
DR OrthoDB; 54358at2759; -.
DR Proteomes; UP000006882; Chromosome g8.
DR ExpressionAtlas; A0A251N3W1; differential.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0007017; P:microtubule-based process; IBA:GO_Central.
DR CDD; cd21203; CH_AtKIN14-like; 1.
DR CDD; cd01366; KISc_C_terminal; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972:SF39; KINESIN-LIKE PROTEIN KIN-14I; 1.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00033; CH; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 40..162
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 392..717
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 194..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..763
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..980
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 474..481
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1008 AA; 111179 MW; 3653FDD25F17E2B1 CRC64;
MAAGGTLSFS VASMVEDVLQ QHGTRVGDLN LESRKAEEAA SRRNEAAGWL RKMIGVVVAK
DLPAEPSEEE FRLGLRSGII LCNAINKVQT GAVPKVVESP CDSALIPDGA ALSAFQYFEN
VRNFLVAIQE MGLPTFEASD LEQGGKSARV VNTVLALKSY SDWKQTGGNG IWKFGGNIKP
TTSAKSFVRK NSEPFTNSLS RTSSMNEKPL SAQASDLDSN KMSSSRSFSM LVRALLLDKK
PEEVPVMVES VLSKLVEEFE QRIASQYELT KTTLKDAAVS HSKKPSMKFA SGDKMMEDKN
SFDKSYISEE ESKVRLLKQK MIFDRQQRDV QELKQTLHTT KSGIQFMKMK FHEEFNNIGL
HIHSLAHAAS GYHRVLEENR KLYNQVQDLK GSIRVYCRVR PFLSGLSNYM STVDHIEDGN
ITINIPSRHG KGRRSFNFNK VFGPSATQAD VFSDMHPLIR SVLDGYNVCI FAYGQTGSGK
TYTMTGPREL TEKSQGVNYR ALGDLFLIAD QRKDTFNYDV SVQMIEIYNE QVRDLLVTDG
TNKRLEIRNS SQTGLSVPDA NLIRVSSTSD VIDLMNLGQR NRVVGATALN DRSSRSHSCL
TVHVQGRDLT SGAILRGCMH LVDLAGSERV DKSEVTGDRL KEAQHINRSL SALGDVIASL
AQKNSHVPYR NSKLTQLLQD SLGGQAKTLM FVHISPEPDA VSETISTLKF AERVATVELG
AARVNKDSTD VKALKEQIAG LKAALARKEE EDEHNKRPAS GGSDKYRTKA SELSPFHSKH
QGTDMLGNQI GCRQPMGNVV ITESHNNSAS RQKRESFDLD ELLVNSPPWP PVESPSQNYG
EDDKEIGSGE WVDKVMVNKQ EAASRAGNPL GCWGADNGNL SDVFYQKYLQ DSSKVYPEQS
YNMFMGSNGF NVASTDDMDD LDAATSDSSE PDLLWQFNQT KLTNMGNGIG SKTKKSNAKQ
VKSPDLSKSF NPSSLGPSPS RKPLNGVPHR IARQPAPAEM KRKAGNRK
//
