ID A0A251N7R2_PRUPE Unreviewed; 763 AA.
AC A0A251N7R2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=PRUPE_7G067200 {ECO:0000313|EMBL:ONH95380.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONH95380.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONH95380.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004323}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CM007657; ONH95380.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251N7R2; -.
DR EnsemblPlants; ONH95380; ONH95380; PRUPE_7G067200.
DR Gramene; ONH95380; ONH95380; PRUPE_7G067200.
DR Proteomes; UP000006882; Chromosome g7.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR PANTHER; PTHR11062; EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED; 1.
DR PANTHER; PTHR11062:SF268; FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR Pfam; PF03016; Exostosin; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022676};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 121..154
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 125..135
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 144..153
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 763 AA; 86438 MW; ADA73C50AF65563F CRC64;
MLSIQKWKCS WSQIATIASI VALASIILGS IVHLFWFPLV PSFNYFSQAQ NSCVPINGSA
EAVIDNVKGN FKPPIDLDRQ FPSDLHKAVV FRGAPWKAEI GRWLSGCDPI SDEVNIVEVI
GGSGCKNDCS GQGVCNRELG QCRCYHGYSG EGCSERLQLE CNYPGSPDQP YGRWVVSICS
AHCDTTRAFC FCGEGTKYPN RPVAEACGFQ VQLPSEPGAP KLTDWAKADL DNVFTKNGSK
PGWCNVDPAE VYAHKVQFKE ECDCKYDCFW GRFCEVPVLC TCINQCSGHG HCRGGFCQCD
NGWYGIDCSI PSVTSSVREW PQWLRPAQVD VPDSSHLPGK VVNLNAVVKK KRPLIYVYDL
PPDFNSLLLE GRHFRLECVN RIYDGKNSTL WTDQLYGAQV ALYESILASP YRTLNGEEAD
FFFVPVLDSC IITRADDAPH LSMQEHKGLR SSLTLEYYRK AYDHIVEQYP FWNRSSGRDH
IWFFSWDEGA CYAPKEIWNS MMLVHWGNTN LKHKHSTTAY WADNWDTIPS DKRGNHPCFD
PDKDLVLPSW KSPDVNSLSS KLWARSHDTR KTLFYFNGNL GPAYPNGRPE ASYSMGIRQK
LAEEFGSSPN KEGKLGKQHA EDVIVTPLRS ENYHGDLASS IFCGVFPGDG WSGRMEDSIL
QGCIPVVIQA FNETEIKFRL ENVQKIWQRF LYRDSIMLEA ERQKTDFGHM EDWAAQFSQL
IEDDVVATFV QVLHYKLHND PWRQHVHVKK EFGLPQECLY KGN
//
