ID A0A251NZ44_PRUPE Unreviewed; 234 AA.
AC A0A251NZ44;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Vacuolar iron transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=PRUPE_6G329900 {ECO:0000313|EMBL:ONI04608.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI04608.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI04608.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CCC1 family.
CC {ECO:0000256|ARBA:ARBA00007049}.
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DR EMBL; CM007656; ONI04608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251NZ44; -.
DR STRING; 3760.A0A251NZ44; -.
DR EnsemblPlants; ONI04608; ONI04608; PRUPE_6G329900.
DR Gramene; ONI04608; ONI04608; PRUPE_6G329900.
DR eggNOG; KOG4473; Eukaryota.
DR OrthoDB; 396206at2759; -.
DR Proteomes; UP000006882; Chromosome g6.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0006880; P:intracellular sequestering of iron ion; IBA:GO_Central.
DR InterPro; IPR008217; Ccc1_fam.
DR PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR PANTHER; PTHR31851:SF60; VACUOLAR IRON TRANSPORTER HOMOLOG 2.1; 1.
DR Pfam; PF01988; VIT1; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 24580 MW; A4BE701D09F17DFD CRC64;
MAGQGALEQA STNHIEIPVY GNVADQPRQQ SQRPEDEEDE TFDYSQRTQW LRAAVLGAND
GLVSVASLMM GVGAVKQDVK AMLLAGFAGL VAGACSMAIG EFVSVYTQYD IEVSQMKRDE
TRTNGAATEN AQEAKKKKLQ LPNPAQAAMA SAIAFSIGAV VPLLGAAFIS EHKVRLAVVV
VLATVALVVF GGVGARLGRT SMMKSCARVL VGGWMAMAIT FGLTKLIGSG GLEM
//
