ID A0A251PC93_PRUPE Unreviewed; 507 AA.
AC A0A251PC93;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=MPN domain-containing protein {ECO:0000259|PROSITE:PS50249};
GN ORFNames=PRUPE_5G222900 {ECO:0000313|EMBL:ONI09194.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI09194.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI09194.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M67C family.
CC {ECO:0000256|ARBA:ARBA00010981}.
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DR EMBL; CM007655; ONI09194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251PC93; -.
DR STRING; 3760.A0A251PC93; -.
DR EnsemblPlants; ONI09194; ONI09194; PRUPE_5G222900.
DR Gramene; ONI09194; ONI09194; PRUPE_5G222900.
DR eggNOG; KOG2880; Eukaryota.
DR OrthoDB; 463685at2759; -.
DR Proteomes; UP000006882; Chromosome g5.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0061578; F:K63-linked deubiquitinase activity; IEA:InterPro.
DR GO; GO:0140492; F:metal-dependent deubiquitinase activity; IEA:InterPro.
DR CDD; cd08066; MPN_AMSH_like; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR044098; STAMBP/STALP-like_MPN.
DR InterPro; IPR015063; USP8_dimer.
DR PANTHER; PTHR12947; AMSH-LIKE PROTEASE; 1.
DR PANTHER; PTHR12947:SF19; AMSH-LIKE UBIQUITIN THIOESTERASE 1; 1.
DR Pfam; PF01398; JAB; 1.
DR Pfam; PF08969; USP8_dimer; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR SUPFAM; SSF140856; USP8 N-terminal domain-like; 1.
DR PROSITE; PS50249; MPN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 333..461
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
SQ SEQUENCE 507 AA; 57482 MW; 6F4BEADA041921CE CRC64;
MRSSCSDRIN IAASAQKLDV DNRIPLRIYF RIANNILKQA DIFRQERNII DLYIMLLRFS
SLVSETIPCH RDYRASVQRE KVFLKKKLFN ALNELEELKP AVKQKNDEFN RRNENQNNGW
GRNHQIAAVI QSPLKKQTLS SYDLTKAGQF SYQTPRAQQV SYSRPVEDQF RKLSVSIPLP
REETLSRHSI LGPNGLHGQW QPPRSDIGVR YPSILDLTPI EIPRLGQSIE EEHTIIKDTS
NSEPEKSTLD PILTQNTDDG PMLPTEELHS LISFESTETP DHTKIIRQPS PPPVLAEVQD
LIPAVSPQVP EVECGLETLS SDDLLRAESP LQLHISTTMM EHFMKLAKSN TDKNLETCGV
LAGSLKNRKF FVTALIIPKQ ESTSDSCQTT NEEEIFEVQD KQSLFPLGWI HTHPTQSCFM
SSIDLHTHYS YQIMLPEAVA IVMAPKGGTR THGIFRLTTP GGMSVIRQCQ QRGFHPHDQP
PDGGPIYKTC ADVYMNPNLK FDVIDLR
//
