ID A0A251PRK5_PRUPE Unreviewed; 649 AA.
AC A0A251PRK5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 13.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN ORFNames=PRUPE_4G201000 {ECO:0000313|EMBL:ONI13075.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI13075.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI13075.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
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DR EMBL; CM007654; ONI13075.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251PRK5; -.
DR EnsemblPlants; ONI13075; ONI13075; PRUPE_4G201000.
DR Gramene; ONI13075; ONI13075; PRUPE_4G201000.
DR Proteomes; UP000006882; Chromosome g4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF269; FORMIN-LIKE PROTEIN 5; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..649
FT /note="FH2 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012264781"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 462..649
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 173..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..449
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 70290 MW; F9CF346BC1160AA8 CRC64;
MTIQQQIGLM RTSCFIVLVI LLCASTSISS EERKITEEVF LSQLVDPATG KIDGDMAQLL
WISCQVDLVH LTEAIEHLHL WLEEETSGGT DEISSKRQSS GKERFQKLIS VLHPEVKQTL
SDCLRRHGLL SRVSGEEGAS KIWYTKYIES LFPRLYVPRR NLGSESLQSS AEVASPAPAA
GSAQLSPVPS AAPTPSTSHT PRSRRPAAAF FPSVSKNSTV QASEPDAGLN VQEDKGRDDR
KKIVIAVVVT ASVTLVVAAV FFLCCTKICR TGKKDGQNDE RPLLSLSLTD SSGSSYKSYV
LGNSMKEVKL DHQSLESGST GGASKFDTSS NINGLVPPPP GRPPTGLPTL KAPPGRANPL
PPEPPSSFKP PPSRNGPPPP PPPVPPSTLK VPPSTLKPSG SAGPPPPPPP PPGPPPPPPP
KIGVPPPRPP QSMPFGSKVA RPPPLAPKRP SNAASGEVGG SDAEGDAPKT KLKPFFWDKV
LANPDHSMVW HQIKSGSFQF DENMIETLFG YNAAEKNKNE RKKESTFQDP SPHLIQIINP
KKAQNLSILL RALNVTVEEV CDAIREGNEL PSEFLQTLLK MAPTQEEELK LRLFNGQLSQ
LGPAERFLKA LIEIPFAFKR LEALLFMCTL QEEVTTLKES FATLEVNFY
//
