ID A0A251R0U6_PRUPE Unreviewed; 425 AA.
AC A0A251R0U6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=5'-3' exonuclease domain-containing protein {ECO:0000259|SMART:SM00475};
GN ORFNames=PRUPE_1G206500 {ECO:0000313|EMBL:ONI29626.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI29626.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI29626.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
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DR EMBL; CM007651; ONI29626.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251R0U6; -.
DR EnsemblPlants; ONI29626; ONI29626; PRUPE_1G206500.
DR Gramene; ONI29626; ONI29626; PRUPE_1G206500.
DR eggNOG; ENOG502QSF6; Eukaryota.
DR Proteomes; UP000006882; Chromosome g1.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 113..383
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 425 AA; 47258 MW; E3CF1C8EE925434F CRC64;
MNVKWCYEFM ASSHSSLLHI HSFSLRRSFR LFARSFSSIQ SPKKLDSLRF SPIKSPKGYC
NISCSFNSAL PGVVRENGDA AFYSKSEQVL CGDMPLGSVK QEEKTVNSNP SDGRVMLIDG
TSIIYRAYYK LLAKLHHGHL SHADGNGDWV LTIFSALSLI IDVLKFTPSH VAVVFDHDGL
NFRHTLYPAY KSNRPPTPDT IVQGLQYLKA SIKAMSIKVI EVPGVEADDV IGTLAVRSVD
TGYKVRVVSP DKDFFQILSP SLRLLRIAPR GFDMVSFGME EFAIKYGSLQ PSQFVDVISL
VGDKCDNIPG VDGIGNVHAV QLITKFGTLE NLLHCVDQVE EERIRKILIT SADQAVLSKN
LALLRSDLPF YMVPFTTNDL AFQKPEDNGE KFTSLLTAIS AYAEGFSADP IIRRAFYLWN
KLGKT
//
