ID A0A251R4W7_PRUPE Unreviewed; 404 AA.
AC A0A251R4W7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|Pfam:PF13456};
GN ORFNames=PRUPE_1G291700 {ECO:0000313|EMBL:ONI31091.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI31091.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI31091.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM007651; ONI31091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251R4W7; -.
DR EnsemblPlants; ONI31091; ONI31091; PRUPE_1G291700.
DR Gramene; ONI31091; ONI31091; PRUPE_1G291700.
DR Proteomes; UP000006882; Chromosome g1.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR036396; Cyt_P450_sf.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR24282:SF20; CYTOCHROME P450 CYP749A22-LIKE; 1.
DR PANTHER; PTHR24282; CYTOCHROME P450 FAMILY MEMBER; 1.
DR Pfam; PF00067; p450; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 330..402
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
SQ SEQUENCE 404 AA; 45661 MW; 36839BB187DC3820 CRC64;
MTASVETMLV RWKKHEGKEI EVFEEFRLLT SEVVSRTAFG SSYLEGKNLF EMLMKLYFLI
FKNLFKFRFP GISLLKPKDE VESKKLEKGI REGIIEIVKK REEKAIMIGE TDSFGNWQEE
ARKGILQIFG KQTPNSDGLA KLKTIGMIIN ESLWLYPPIV SIARKVEREV RLGKLIVPAN
VEIFIPSLAI HHEPQLWGED AHLFKWERFS EGIAKATKNK IAAFLPFGMG PKVTGYSTDF
EGLLEDCQIW KPTSNEKILS NEQRIRRHLT GNCACDYCKW PIESTLHILR DCSRARKDWF
QAIINTNSGA NKVQVLLAWV PPEIGLVKLN IDGSCRGSTG AIGAGGVLRD HLGQWIGGFA
VNLGQGEVLE AELWGLFFGL NLAIEKKLHD IVIEMDSDTT VLLI
//
