ID A0A251RVX0_HELAN Unreviewed; 1119 AA.
AC A0A251RVX0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=HannXRQ_Chr17g0568151 {ECO:0000313|EMBL:OTF87994.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTF87994.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
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DR EMBL; CM007906; OTF87994.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251RVX0; -.
DR InParanoid; A0A251RVX0; -.
DR OMA; PRINDTR; -.
DR Proteomes; UP000215914; Chromosome 17.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR45835:SF105; IPP TRANSFERASE; 1.
DR PANTHER; PTHR45835; YALI0A06105P; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918,
KW ECO:0000313|EMBL:OTF87994.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 235..414
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 756..919
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 1119 AA; 129079 MW; 9451E3093B4B5BC7 CRC64;
MNAQEAQANN EVVNGTFFIN NQPASVLFDS GADKSFVSLS FETMLRVSRT KLGKPLTVEV
ASGEPIVLNS VLRNCQLNLN DHIFPIDLTP MQLGSFDAIV GMDWLSKHRA EIVCSEKIVR
VPLSTGEILQ VRGEKPAGGL KLMSCFKARK YLRKHYVAFL AHVTADKGKG KTISDIPVVR
DYSEVFPEDL PGLPPACQVE FRIDLVPGAN PIARAPYRLA PSEMQELSKQ LQELSDKGFI
RPSFSPWGAP VLFVKKKDGS FRMCIDYREL NKLTIKNRYP LPRIDDLFDQ LQGASYFSKI
DLRSGYHQLR VHEEDIPKTT FRTRYGHYEF TVMPFGLTNA PAVFMDLMNR VCNPYLDKFI
IIFIDDILIY SKTRAEHEQH LRLTLELLKK EQLFAKFSKC EFWLKEVQFL GHIVNEQGIH
VDPSKISAIK DWDTPTTPIE VHSFLGLAGY YRRFIENFSK IAVPLTALTQ KNKPFDWGVK
QEEAFLTLKQ KLCDAPVLTL PEGNDDFVVY CDASKLGLGC VLMQRNKVIA YASRQLKIHE
KNYTTHDLEL GAVVFALKIW RHYLYGTKCV VFTDHKSLQH IFNQKELNMR QRRWVELLND
YDCEIRYHPG KANVVADALS RKERTKLHCV RVQYVIQTDI QARISQAQQA CVSQGLMDKE
LPYHITPALE LKDNGSYYFM DRLWVPSQDN LRTLLMDEAH KSRYSIHPGS DKMYKDLRIQ
YWWPGMKKDI ALYVSKCLTC LKVKAEHQRP SGLLEQPEIP VWKWENITMD LITKLPRTKK
GHDAIWVVVD RLTKSAHFLP IREDFLADKL AQIYVDEIVA RHGVPLNIIS DRDARFTSHF
WRTMQSAMGS QLNLSTAYHP QTDGQSERTI QTLEDMFRAC VIDFGGSWDS HLPLIEFSYN
NSYHSSINMA PFEALYGRKC RSPVCWNEIG EAQLTGPALI LETTEKVKKD RDNLQTARNR
QKSYVDLKRK PLDFQVGDRV LLKVSPWKGV IRFGKKGKLA PRYVGPFKIV ERIGKVAYRL
ELPPELGNVH PTFHVSNLKR CLADENLHIP LDEIRVDKTL KFVEKPVEIM EREVKWLKRK
RIPLVKVRWE SKRGPEFTWE REDQMKAKYP HLFPSVSSK
//
