ID A0A251S5G4_HELAN Unreviewed; 320 AA.
AC A0A251S5G4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=WAT1-related protein {ECO:0000256|RuleBase:RU363077};
GN ORFNames=HannXRQ_Chr16g0532111 {ECO:0000313|EMBL:OTF93366.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTF93366.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363077}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU363077}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000256|ARBA:ARBA00007635, ECO:0000256|RuleBase:RU363077}.
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DR EMBL; CM007905; OTF93366.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251S5G4; -.
DR InParanoid; A0A251S5G4; -.
DR OMA; ITICGAM; -.
DR Proteomes; UP000215914; Chromosome 16.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218:SF319; EAMA DOMAIN, JMJC DOMAIN, WAT1-RELATED PROTEIN-RELATED; 1.
DR PANTHER; PTHR31218; WAT1-RELATED PROTEIN; 1.
DR Pfam; PF00892; EamA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363077};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transmembrane {ECO:0000256|RuleBase:RU363077};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363077}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 44..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 179..200
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 212..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT DOMAIN 150..287
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 320 AA; 35216 MW; 2327EFF8B3EC19B1 CRC64;
MTRRRWSWMN ELLPFVAMLM TTCLDMGALT LVKAAMDGGL SIIVYIVYHS ALGTFILLPF
FIIHIYRNIG RPQLTFHIML RFFILGLLGM EKIDMRSSVS VAKLSGTIIT ICGAMVFTFY
QGPQLFVTIR SPGSPDDQIL LSQPSNWVFG GLMIFIGGTF GCIWNVLQSA IAKEFPDQFT
IVFFFCLFGT IQCTALSPFL EPNPSAWLVQ SGIGTIAVVF GAVYSVGIRI SILTWCLEKK
GPVYVAMFSP LSIVIAIIMG VTFLGDALHI GSAIGAVIII AGFYVVMWGQ VQEKNKLEDK
HLDVANESGL SDQTAPLLFP
//
