ID A0A251SZI2_HELAN Unreviewed; 516 AA.
AC A0A251SZI2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Proteasome endopeptidase complex {ECO:0000313|EMBL:KAF5776134.1};
DE EC=3.4.25.1 {ECO:0000313|EMBL:KAF5776134.1};
DE SubName: Full=Putative associated molecule with the SH3 domain of STAM 1 {ECO:0000313|EMBL:OTG03696.1};
GN Name=AMSH1 {ECO:0000313|EMBL:OTG03696.1};
GN ORFNames=HannXRQ_Chr12g0354231 {ECO:0000313|EMBL:OTG03696.1},
GN HanXRQr2_Chr12g0520881 {ECO:0000313|EMBL:KAF5776134.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG03696.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5776134.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5776134.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG03696.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG03696.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5776134.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5776134.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M67C family.
CC {ECO:0000256|ARBA:ARBA00010981}.
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DR EMBL; MNCJ02000327; KAF5776134.1; -; Genomic_DNA.
DR EMBL; CM007901; OTG03696.1; -; Genomic_DNA.
DR STRING; 4232.A0A251SZI2; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr12g0520881; mRNA:HanXRQr2_Chr12g0520881; HanXRQr2_Chr12g0520881.
DR Gramene; mRNA:HanXRQr2_Chr12g0520881; mRNA:HanXRQr2_Chr12g0520881; HanXRQr2_Chr12g0520881.
DR InParanoid; A0A251SZI2; -.
DR OMA; GLHGQWQ; -.
DR OrthoDB; 463685at2759; -.
DR Proteomes; UP000215914; Chromosome 12.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0061578; F:K63-linked deubiquitinase activity; IEA:InterPro.
DR GO; GO:0140492; F:metal-dependent deubiquitinase activity; IEA:InterPro.
DR CDD; cd08066; MPN_AMSH_like; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR044098; STAMBP/STALP-like_MPN.
DR InterPro; IPR015063; USP8_dimer.
DR PANTHER; PTHR12947; AMSH-LIKE PROTEASE; 1.
DR PANTHER; PTHR12947:SF19; AMSH-LIKE UBIQUITIN THIOESTERASE 1; 1.
DR Pfam; PF01398; JAB; 1.
DR Pfam; PF08969; USP8_dimer; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR PROSITE; PS50249; MPN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KAF5776134.1};
KW Proteasome {ECO:0000313|EMBL:KAF5776134.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 342..472
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
FT REGION 112..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 58219 MW; 6C076E108A066DD0 CRC64;
MRSTINVAAN TQKINVDNRI SLRYYFRIAD NILRQAAIFR EEKNIIDLYI MLLRFSSLAT
ETIPYHRDYS ASLQRDKIYL KKKSLSAITE LEELKPAVLQ KINDLSRKHA YQSNGWTPQN
KLLEPSKPPP ERYPLHQQTS TQSYAGTINK APTPQVKVHG HVYRDSRNLV YSAPYPLDEQ
TRQLSVNIPR AKEETLSRHS ILGPNGLYGQ WQPPTINVAV YYPKNVDLTP VEFQSEKKLI
SLEDGVPIER NSSNLEHENS SLETVVSANN NKKPQADEPD LLISFEEKIE TPPVPLDIIR
QPSPPPVLAQ VHDLVSPSLD TGLTNGSEKP SDGVCSESPL ELHISSKVMD HFMKMAKPNT
NKDLETCGIL AGSLKNRKFY VTALIIPKQE GTANSCQATN EEEIFEVQDK RSLFPLGWIH
THPTQSCFMS SIDVHTHYAY QIMLPEAIAI VMAPRDSSRN HGIFRLTTPG GMGVIRNCPH
RGFHAHDAPS DGSPIYKQCT DVYINPKLKF DVIDLR
//
