ID A0A251T2X4_HELAN Unreviewed; 357 AA.
AC A0A251T2X4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Deacetoxyvindoline 4-hydroxylase {ECO:0000313|EMBL:KAF5778385.1};
DE EC=1.14.11.20 {ECO:0000313|EMBL:KAF5778385.1};
DE SubName: Full=Putative 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein {ECO:0000313|EMBL:OTG05470.1};
GN ORFNames=HannXRQ_Chr12g0373891 {ECO:0000313|EMBL:OTG05470.1},
GN HanXRQr2_Chr12g0546811 {ECO:0000313|EMBL:KAF5778385.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG05470.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5778385.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5778385.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG05470.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG05470.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5778385.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5778385.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
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DR EMBL; MNCJ02000327; KAF5778385.1; -; Genomic_DNA.
DR EMBL; CM007901; OTG05470.1; -; Genomic_DNA.
DR STRING; 4232.A0A251T2X4; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr12g0546811; mRNA:HanXRQr2_Chr12g0546811; HanXRQr2_Chr12g0546811.
DR Gramene; mRNA:HanXRQr2_Chr12g0546811; mRNA:HanXRQr2_Chr12g0546811; HanXRQr2_Chr12g0546811.
DR InParanoid; A0A251T2X4; -.
DR OMA; NREGYWY; -.
DR OrthoDB; 1057251at2759; -.
DR Proteomes; UP000215914; Chromosome 12.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR10209:SF775; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR10209; OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682,
KW ECO:0000313|EMBL:KAF5778385.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914}.
FT DOMAIN 205..307
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 357 AA; 40303 MW; B1024489247D7A66 CRC64;
MAFTGDDFDR ESELKAFDQT KQGVKGLVDS GITKVPRIFI QPPDVFSQCI TPLHLPVINL
GGFWSDRVRR TEIVKEVREA ARIWGFFQVI NHGIPESVMK EMRDGALRFF DQDHKVKKEW
YVTDSSKKMF YNSNVDLSSS LPVRWRDSFH CRMAPGPPHP EELPPPCRDI LIEYSKQVTK
LGCSLFELLS EALGLGSSHL KDIGCADGLA TICHYYPASP QSELTIGARK HADNDFITVL
LQDHIGGLQF LHKNQWVDVP FVPGALVVNI GDLLQLISND EFMSAEHRVM SSSFGPRVSV
ACFFTTGTVD TGKVFEPIKE LLSEQNPAKY RATTMKEFVQ HSHSKVFDKS SMLHFRI
//
