ID A0A251T8P5_HELAN Unreviewed; 991 AA.
AC A0A251T8P5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=HannXRQ_Chr11g0331101 {ECO:0000313|EMBL:OTG07495.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG07495.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CM007900; OTG07495.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251T8P5; -.
DR InParanoid; A0A251T8P5; -.
DR OMA; GRNWAVV; -.
DR OrthoDB; 991910at2759; -.
DR Proteomes; UP000215914; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF105; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 3.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OTG07495.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..991
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012987691"
FT TRANSMEM 598..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 657..938
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 685
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 991 AA; 109349 MW; 9B2FD5BA1A86FFD0 CRC64;
MLLVILCVSL LPFAFASINT TCLPPEEVDA LREIGRQLGK DWDFRQDPCR GWEISSDGEH
ENNVTCNLES NHTICHVVSI SLKGQSLSGI LPVEFVNLPY LLNLDLARNC LRGTIPPQWG
SMQRIVDISL LVNRLNGSIP KELGNISTLK SLSVEDNMMS GAIPDDLGNL TSIERLVLSS
NFFTGKLPLS FANMINMTEF RISGNNFSGK IPDFIGEWTS LTTLRIQASG LEGPIPSSIT
LLDSLTDLRI SDLRGPDTVC PPFSNTARFK HLFLRSCNLI GQLPVLPQSL ASSLKVLDFS
FNKLNGSIPT SFSELNDTDY IYLTGNLLSG NVPDWMLSVG KKIDLSYNNF TYNNPPSCHV
RETNLFASFS DDTISKKVSC LRSSDCQTNW SSMYIDCGGD GLSIGNDSYE SDLEDGGASF
FTSTESRWGF SNTGQFLGND VSVDNYTVKN TSRLLMNNPG LYMSARVSSL SLTYYGFCLV
NGSYNVSLHF AEIIFTDDET YSSLGRRVFD IYIQGERVEM DFDISNEAGG VGKEIVKSYT
VNVNATLFIR LSWAGKGTTS IPSRGVYGPL ISAISVKSNF WVPPKDGPLQ GNGNGVSAGT
VAGIVVGTLC LIILILGALW WRGCLRCRNA MQLELNGLEL NTCTFTLRQI KTATNNFDVA
NKIGEGGFGS VYKGILPDGT LIAVKQLSSR SKQGNREFLN ELGMISALQH PHLVKLHGCC
IEGNQLLLAY EYMENNSLAC ALYGPKEWQL ELNWPTRYRI CLQIAKGLAF LHEESRLKIV
HRDIKTTNVL LDKNLNAKIS DFGLAKLDED DNTHISTRIA GTYGYMAPEY ALRGYLTDKA
DVYSYGIVLL EIVSGTSNIP DRTKENNFVL IDRAISLKTT GNLMELVDPK LNSKYDIQEM
MVVINLAILC IAISPINRPT MSSVVSMLEG RIVPQEYVVE QGVQAAEIDP HTMMKQHKDT
NESQITKMSI RCNDSSKSVV DLYPVDGFSD I
//
