ID A0A251TBD5_HELAN Unreviewed; 589 AA.
AC A0A251TBD5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Amino acid/polyamine transporter I, cationic amino acid transporter {ECO:0000313|EMBL:KAF5770532.1};
DE SubName: Full=Putative cationic amino acid transporter 6 {ECO:0000313|EMBL:OTG08455.1};
GN Name=ATCAT6 {ECO:0000313|EMBL:OTG08455.1};
GN ORFNames=HannXRQ_Chr11g0341961 {ECO:0000313|EMBL:OTG08455.1},
GN HanXRQr2_Chr14g0660471 {ECO:0000313|EMBL:KAF5770532.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG08455.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5770532.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5770532.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG08455.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG08455.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5770532.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5770532.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
CC {ECO:0000256|ARBA:ARBA00008572}.
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DR EMBL; MNCJ02000329; KAF5770532.1; -; Genomic_DNA.
DR EMBL; CM007900; OTG08455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251TBD5; -.
DR STRING; 4232.A0A251TBD5; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr14g0660471; mRNA:HanXRQr2_Chr14g0660471; HanXRQr2_Chr14g0660471.
DR Gramene; mRNA:HanXRQr2_Chr14g0660471; mRNA:HanXRQr2_Chr14g0660471; HanXRQr2_Chr14g0660471.
DR InParanoid; A0A251TBD5; -.
DR OMA; FCLYLMY; -.
DR OrthoDB; 1421713at2759; -.
DR Proteomes; UP000215914; Chromosome 11.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR PANTHER; PTHR43243:SF103; CATIONIC AMINO ACID TRANSPORTER 6-RELATED; 1.
DR PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF13906; AA_permease_C; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 509..559
FT /note="Cationic amino acid transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13906"
SQ SEQUENCE 589 AA; 64451 MW; 57876FBEAF94CEBE CRC64;
MRMAIESNRS SFSSVKSYVN ALRDTPRRVV RRAGSVTTTF DETSHVRFRY GGSMRKTLRW
YDLICFGVGG MVGAGVFVTT GTASHDKAGP AVVLSYAIAG FCALLSAFCY TEFAVHMPVA
GGAFSYIRVT FGEFMAFLTG ANLIMDYVFS NAAVARSFTT YLGTAIGVSA ESKWRITITS
LPKGFNEIDF IAVLVIIILT VIICYSTRES SVLNMILTAL HIIFIMFVII MGFWRGDSKN
FTEPSDPTRP SGFFPFGASG MFNGAALVYL SYIGYDAVST LAEEVKNPVT DIPIGVTGCV
ILVTVLYCLM ATSMSMLLPY DLINPEAPFS GAFVDKSNRL NWVSNVIGVG ASFGILTSLL
VAMLGQARYL CVIGRSNIVP VWFAKVHPKT STPVNASAFL GIFTAVIALF TELDVLLNLV
SIGTLFVFFM VANAVIYRRY VSVETLSPWP TLSFLICFSC TSVIFTLLWW LVPPGKPKFF
VLGACFIVIC GLVVVFNYAV PQARKPEFWG VPLMPWIPCV SIFLNIFLLG NLDGPSYARF
GFFSALAVVV YLAYSVHASF DSEEEGIVNL ESGIKESIEL EDLTPKLQK
//
