ID A0A251U1K9_HELAN Unreviewed; 540 AA.
AC A0A251U1K9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acid--thiol ligase {ECO:0000313|EMBL:KAF5793085.1};
DE EC=6.2.1.- {ECO:0000313|EMBL:KAF5793085.1};
DE SubName: Full=Putative 4-coumarate--CoA ligase 2 {ECO:0000313|EMBL:OTG16702.1};
GN Name=4CL2 {ECO:0000313|EMBL:OTG16702.1};
GN ORFNames=HannXRQ_Chr09g0274301 {ECO:0000313|EMBL:OTG16702.1},
GN HanXRQr2_Chr09g0413441 {ECO:0000313|EMBL:KAF5793085.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG16702.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5793085.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5793085.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG16702.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG16702.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5793085.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5793085.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Phytoalexin biosynthesis; 3,4',5-trihydroxystilbene
CC biosynthesis; 3,4',5-trihydroxystilbene from trans-4-coumarate: step
CC 1/2. {ECO:0000256|ARBA:ARBA00004930}.
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DR EMBL; MNCJ02000324; KAF5793085.1; -; Genomic_DNA.
DR EMBL; CM007898; OTG16702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251U1K9; -.
DR SMR; A0A251U1K9; -.
DR STRING; 4232.A0A251U1K9; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr09g0413441; mRNA:HanXRQr2_Chr09g0413441; HanXRQr2_Chr09g0413441.
DR Gramene; mRNA:HanXRQr2_Chr09g0413441; mRNA:HanXRQr2_Chr09g0413441; HanXRQr2_Chr09g0413441.
DR InParanoid; A0A251U1K9; -.
DR OMA; YIMPKFD; -.
DR OrthoDB; 1404660at2759; -.
DR UniPathway; UPA00372; UER00547.
DR Proteomes; UP000215914; Chromosome 9.
DR GO; GO:0016207; F:4-coumarate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016405; F:CoA-ligase activity; IBA:GO_Central.
DR GO; GO:0009698; P:phenylpropanoid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05904; 4CL; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF370; 4-COUMARATE--COA LIGASE 2-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:OTG16702.1};
KW Phenylpropanoid metabolism {ECO:0000256|ARBA:ARBA00023051};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914}.
FT DOMAIN 30..398
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 449..524
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 540 AA; 59210 MW; 38E2E87CC2C27976 CRC64;
MAPEKEIIFR SKLPDIYIPK HLPLHSYCFE NISTFNNRPC LIDGATGVVH TYADVELTSR
KVASAFHQHG INKGDVIMIL LPNSPEFVYS FFGASYLGAV STMANPFFTS AEIIKQAKAS
NAKIIVTQAS HVPKIKEYAA ENSIKIVCID SAPEGCLHFT ELVSGDETKL PEVEISSDDV
VALPYSSGTT GLPKGVMLTH KGLVTSVAQQ VDGENPNLWI HSEDVLMCVL PLFHIYSLNS
ILLCGLRAGA AILIMQKFDI VPFLELIEKY KVTIGPFVPP IVLAIANNEE VVDKYDLSSM
RTVMSGAAPL GKELEDMVRR KFTNAKLGQG YGMTEAGPVL AMCLAFAKEP YEIKSGACGT
VVRNAEMKIV DPETGLSLPR NQRGEICIRG DQIMKGYLND PESTKTTIDS DGWLHTGDIG
LIDDDDELFI VDRLKELIKY KGFQVAPAEL EALLLTHPQI SDVAVVPMVN EAAGEVPVAF
VVKTKDSSVT EDDIKQFVHK QVVFYKRINR VFFIDTIPKS PAGKILRKEL RAKLAAGVPN
//
