ID A0A251U331_HELAN Unreviewed; 388 AA.
AC A0A251U331;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:KAF5794315.1, ECO:0000313|EMBL:OTG17767.1};
DE EC=1.1.1.1 {ECO:0000313|EMBL:KAF5794315.1};
GN ORFNames=HannXRQ_Chr08g0215811 {ECO:0000313|EMBL:OTG17767.1},
GN HanXRQr2_Chr08g0326701 {ECO:0000313|EMBL:KAF5794315.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG17767.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5794315.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5794315.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG17767.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG17767.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5794315.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5794315.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; MNCJ02000323; KAF5794315.1; -; Genomic_DNA.
DR EMBL; CM007897; OTG17767.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251U331; -.
DR STRING; 4232.A0A251U331; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr08g0326701; mRNA:HanXRQr2_Chr08g0326701; HanXRQr2_Chr08g0326701.
DR Gramene; mRNA:HanXRQr2_Chr08g0326701; mRNA:HanXRQr2_Chr08g0326701; HanXRQr2_Chr08g0326701.
DR InParanoid; A0A251U331; -.
DR OMA; AFCGHCE; -.
DR OrthoDB; 451143at2759; -.
DR Proteomes; UP000215914; Chromosome 8.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IBA:GO_Central.
DR GO; GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR GO; GO:0046294; P:formaldehyde catabolic process; IBA:GO_Central.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF7; ALCOHOL DEHYDROGENASE-LIKE 7; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KAF5794315.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 41..134
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 211..343
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 388 AA; 42077 MW; A5D3D2C239A47128 CRC64;
MAGKTSTNTA GKPIRCRAAI ARKAGEPLVI EEVIVAPPKS REVRIKIICT SLCHSDVTFW
KLEQPPAIFP RILGHEAVGV VESIGEGVHE VVEGDTVIPI FLPDCGECTD CLSVKSNLCS
KLPFSVSPYM DREKTSRFTD LNGETLYHFL FVSSFSEYTV VDIGHVTKID PQTPPNRACL
LSCGVSTGVG AAWKTANVET GTTVAIFGLG AIGLAVAEGA RLCGAKRIVG VDVNQDKFEL
GKKFGVTDFV NSRNCGDKSV SQVIMEMTDG GADYCFECVG MSSLVHEAYA SCRKGWGKTV
VLGVDQPGAM LTFTSFEVLH SGKTLMGSLF GGIKPKSDIP ILIKRYMDKE LQLDEFVTHE
VDFEDINKAF DLLLEGKSLR CVIWMKSD
//
