ID A0A251U4A6_HELAN Unreviewed; 1398 AA.
AC A0A251U4A6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-NOV-2023, entry version 27.
DE SubName: Full=ABC-type xenobiotic transporter {ECO:0000313|EMBL:KAF5794810.1};
DE SubName: Full=Putative bile salt export pump {ECO:0000313|EMBL:OTG18175.1};
GN Name=ABCBB {ECO:0000313|EMBL:OTG18175.1};
GN ORFNames=HannXRQ_Chr08g0220221 {ECO:0000313|EMBL:OTG18175.1},
GN HanXRQr2_Chr08g0332321 {ECO:0000313|EMBL:KAF5794810.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG18175.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5794810.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5794810.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG18175.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG18175.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5794810.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5794810.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MNCJ02000323; KAF5794810.1; -; Genomic_DNA.
DR EMBL; CM007897; OTG18175.1; -; Genomic_DNA.
DR EnsemblPlants; mRNA:HanXRQr2_Chr08g0332321; mRNA:HanXRQr2_Chr08g0332321; HanXRQr2_Chr08g0332321.
DR Gramene; mRNA:HanXRQr2_Chr08g0332321; mRNA:HanXRQr2_Chr08g0332321; HanXRQr2_Chr08g0332321.
DR InParanoid; A0A251U4A6; -.
DR OMA; DSAYNSH; -.
DR OrthoDB; 5487044at2759; -.
DR Proteomes; UP000215914; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24222; ABC TRANSPORTER B FAMILY; 1.
DR PANTHER; PTHR24222:SF52; ABC TRANSPORTER B FAMILY MEMBER 20-RELATED; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 822..851
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 871..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 947..967
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 973..996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1045..1072
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1092..1113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 82..370
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 403..638
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 826..1102
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1149..1386
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1398 AA; 155058 MW; 0FB4E826725CDCDF CRC64;
MMQSRGGLFG WSPPRQQPLT PVSEVSEPPE SPSPYMDASA DAVAPDVEDE VEEMEEIEPP
PEAVPFSRLF ACADRLDWVL MVVGSVAAAA HGTALVVYLH YFAKIVQLLS HGEETPELLF
HRFKELALTL VYIAGGVFAA GWIEVSCWIL TGERQTAVIR SSYVQVLLNQ DMSFFDTYGN
NGDIVSQVLS DVLLIQSALS EKVGNYIHNM ATFFSGLAIG FINCWQIALI TLATGPFIVA
AGGISNIFLH RLAENIQDAY AEAASIAEQA ISYIRTLYAF TNETLAKYSY AASLQATLRY
GILISLVQGL GLGFTYGLAI CSCALQLYVG RVLVTHGKAH GGEIVTALFA VILSGLGLNQ
AATNFYSFEQ GRIAAYRLFE MISRSSSTVK HDGNVLDSVQ GNIEFRNVYF SYLSRPEIPI
LSGFYLTVPA KKTVALVGRN GSGKSSIIPL MERFYDPTLG EVLLDGENIK NLKLEWLRSQ
IGLVTQEPAL LSLSIRDNIA YGRDATLLQI EDAAKIAHAH TFISSLEKGY DTQVGRAGLS
LTEEQKIRLS VARAVLSNPS ILLLDEVTGG LDFEAEKSVQ EALDLLMLGR STIIIARRLS
LIRNADFIAV MEEGQLMEIG THDELIASDG LYAELLRCEE AAKLPRRMPA RTYDPATFQI
EKDSSASHSY QESSSPKFAK SPSLQRASNL HASARSPDSA YNSHESPRNP SPPERTFENG
SHVDGPNNQP SIKRQDSFEM RLPELPKIDV VSIQRQTSHE SDPESPISPL LTSDPNNERS
HSQTFSRPNS HFGDDPVKVK EVKEKRKEPP MWRLVELSFA EWLYAVLGSM GAAIFGSFNP
LLAYVIALIV AEYYKKENHK HMRHEVDKWC LIIACMGVVT VIANFLQHFY FGIMGEKMTE
RVRRMMFSAM LRNEVGWFDE EENSADTLSM RLANDATFVR AAFSNRLSIF IQDSTAVLVA
LLIGMLLQWR LALVALGTLP VLTVSAIAQK LWLAGFSKGI QEMHRKASLV LEDAVRNIYT
VVSFCAGDKV MELYRLQLHK IFTKSFLHGM AIGFAFGFSQ FLLFACNALL LWYTALTYKN
RHVDLPTAIK EYMVFSFATF ALVEPFGLAP YILKRRKSLI SVFEIIDRVP KIDPDDVTAL
KPPNVYGSIE LKNVDFSYPT RPEILVLSNF SLKVNGGQTV AVVGVSGSGK STIISLIERF
YDPVAGQVNL DGRDLKLFNL RWLRNHLGVV QQEPIIFSTT IRENIIYARH NASEAEIKEA
ARIANAHHFI SNLPHGYETH VGMRGVDLTP GQKQRIAIAR VVLKNAPILL LDEASSSIES
ESSRVVQEAL DTLIMGNKTT ILIAHRAAMM RHVDNIVVLN GGRIVEEGSH DSLMSKNGLY
VRLMQPHFGK GLRQHRLL
//
