ID A0A251UGS3_HELAN Unreviewed; 696 AA.
AC A0A251UGS3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Putative SPX domain-containing membrane protein {ECO:0000313|EMBL:OTG22243.1};
DE SubName: Full=SPX domain, major facilitator superfamily, MFS transporter superfamily {ECO:0000313|EMBL:KAF5801172.1};
GN Name=SPXM2 {ECO:0000313|EMBL:OTG22243.1};
GN ORFNames=HannXRQ_Chr06g0169371 {ECO:0000313|EMBL:OTG22243.1},
GN HanXRQr2_Chr06g0244991 {ECO:0000313|EMBL:KAF5801172.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG22243.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5801172.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5801172.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG22243.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG22243.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5801172.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5801172.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; MNCJ02000321; KAF5801172.1; -; Genomic_DNA.
DR EMBL; CM007895; OTG22243.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251UGS3; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr06g0244991; mRNA:HanXRQr2_Chr06g0244991; HanXRQr2_Chr06g0244991.
DR Gramene; mRNA:HanXRQr2_Chr06g0244991; mRNA:HanXRQr2_Chr06g0244991; HanXRQr2_Chr06g0244991.
DR InParanoid; A0A251UGS3; -.
DR OMA; FIMQDEL; -.
DR Proteomes; UP000215914; Chromosome 6.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF79; SPX DOMAIN-CONTAINING MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF03105; SPX; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..692
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..146
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 470..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..487
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 78696 MW; 0C816D132E196BBE CRC64;
MVAFGKKLKE LQIQEWKGSY IDYKLLKKKV KHYARQDEVD GPNREYVLHD FSLMLDEQIE
KIVLFLLKHQ GQLATRLSGL ADRDDEYLSH GPNHDSIVEL REAYREVGRD LLRLLFFVEM
NAIGLRKILK KFDKRLGYKF TSYYVKTRAN HPYSQLRQVF KHVGISAVVG SITRNLADLQ
DVDRRYVSIY DHPNIHISDP IIESIKAAEK RLLNSTDFLH YLGKHAFIMQ DELPSPSSEE
HIVNERYHFM SLLLNLVNTF LYMVNTYIIV PTADDYSLSL GAAATVCGVV IGSMAVAQIF
SSVYFSAWSN KSYIRPLIFS SIVLLMGNTL YALAYDLNSI YVLLIGRLFC GLGSARAVNR
RYISDCVPSK LRMKASAGFV SASALGMACG PALACLFQTQ FKILWFTFNQ DTLPGWFMAF
AWFIYLLWLW LSFREPPLEK EDIVVQHETS GTTVEIGFSE PLLLDFGKNE EDEDQQQEDD
DPSDELSEDN REPVTSIMSA YRLLTPSVKV QLIIYFMLKY AMEILLAESS VVTSYYFVWS
TNNVAMFLAF LGLTVLPVSI FVGSYISNVF EERQVLLASE IMVCLGIVLS FHTIIPYSAP
QYIFSALLTF VSAEVLEGVN LSLLSRVMSS RLSRGTYNGG LLSTEAGTLA RVVADGTITL
AGYWGMSELL NITLLPSLVI CIATIIATSF TYNSLY
//
