ID A0A251UJL0_HELAN Unreviewed; 1574 AA.
AC A0A251UJL0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Transcription elongation factor spt6 {ECO:0000256|PIRNR:PIRNR036947};
GN Name=GTB1 {ECO:0000313|EMBL:OTG22962.1};
GN ORFNames=HannXRQ_Chr06g0177131 {ECO:0000313|EMBL:OTG22962.1},
GN HanXRQr2_Chr06g0259151 {ECO:0000313|EMBL:KAF5802407.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG22962.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5802407.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5802407.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG22962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG22962.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5802407.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5802407.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription elongation factor that enhances transcription
CC elongation by RNA polymerase II (RNAPII).
CC {ECO:0000256|PIRNR:PIRNR036947}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR036947}.
CC -!- SIMILARITY: Belongs to the SPT6 family. {ECO:0000256|ARBA:ARBA00009253,
CC ECO:0000256|PIRNR:PIRNR036947}.
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DR EMBL; MNCJ02000321; KAF5802407.1; -; Genomic_DNA.
DR EMBL; CM007895; OTG22962.1; -; Genomic_DNA.
DR STRING; 4232.A0A251UJL0; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr06g0259151; mRNA:HanXRQr2_Chr06g0259151; HanXRQr2_Chr06g0259151.
DR Gramene; mRNA:HanXRQr2_Chr06g0259151; mRNA:HanXRQr2_Chr06g0259151; HanXRQr2_Chr06g0259151.
DR InParanoid; A0A251UJL0; -.
DR OMA; LCNGFKT; -.
DR OrthoDB; 170310at2759; -.
DR Proteomes; UP000215914; Chromosome 6.
DR GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0031491; F:nucleosome binding; IBA:GO_Central.
DR GO; GO:0034728; P:nucleosome organization; IBA:GO_Central.
DR GO; GO:0032968; P:positive regulation of transcription elongation by RNA polymerase II; IEA:UniProtKB-UniRule.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0140673; P:transcription elongation-coupled chromatin remodeling; IEA:InterPro.
DR CDD; cd09928; SH2_Cterm_SPT6_like; 1.
DR CDD; cd09918; SH2_Nterm_SPT6_like; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.10.650; RuvA domain 2-like; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 2.
DR Gene3D; 1.10.10.2740; Spt6, Death-like domain; 1.
DR Gene3D; 1.10.150.850; Spt6, helix-hairpin-helix domain; 1.
DR Gene3D; 1.10.3500.10; Tex N-terminal region-like; 1.
DR Gene3D; 3.30.420.140; YqgF/RNase H-like domain; 1.
DR InterPro; IPR041692; HHH_9.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR049540; Spt6-like_S1.
DR InterPro; IPR028083; Spt6_acidic_N_dom.
DR InterPro; IPR042066; Spt6_death-like.
DR InterPro; IPR032706; Spt6_HHH.
DR InterPro; IPR035420; Spt6_SH2.
DR InterPro; IPR035018; Spt6_SH2_C.
DR InterPro; IPR035019; Spt6_SH2_N.
DR InterPro; IPR028231; Spt6_YqgF.
DR InterPro; IPR023323; Tex-like_dom_sf.
DR InterPro; IPR023319; Tex-like_HTH_dom_sf.
DR InterPro; IPR017072; TF_Spt6.
DR InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR PANTHER; PTHR10145; TRANSCRIPTION ELONGATION FACTOR SPT6; 1.
DR PANTHER; PTHR10145:SF6; TRANSCRIPTION ELONGATION FACTOR SPT6; 1.
DR Pfam; PF14635; HHH_7; 1.
DR Pfam; PF17674; HHH_9; 1.
DR Pfam; PF14633; SH2_2; 1.
DR Pfam; PF14632; SPT6_acidic; 1.
DR Pfam; PF21710; Spt6_S1; 1.
DR Pfam; PF14639; YqgF; 1.
DR PIRSF; PIRSF036947; Spt6; 1.
DR SMART; SM00316; S1; 1.
DR SMART; SM00732; YqgFc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 2.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF158832; Tex N-terminal region-like; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036947};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR036947};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR036947}.
FT DOMAIN 1132..1202
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1459..1574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..72
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..203
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1481..1497
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1550..1574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1574 AA; 179145 MW; 2C20E82C84BA891B CRC64;
MAGNTILSDE EDEIEVEEDE REEPDGEDVD PGDRDDDEDE EDEEGQDEYE KDGFIVDDID
EEDQDGEEED RADSDEERQR KKKRKKRESE KNYVLDEDDY ELLQDNVGFR RPKVESKKFK
RLKKARADAD EGQSGFSDEE EYDITGKGGR SAEDKIKRSL FDDDEGPPLE DIAEEDQQLE
EEDGDIGEEE DEMADFIVDE EEVDEHGEPT RRRKVNKKKS RQAPGVSSTA IQEAHDIFGD
VDELLRQRKQ GLERISRYDE SGEWRERRLE DEFEPIILSE KYMTESDDRI REIDIPERMQ
ISEESTGPPP TDGISIDDES NWILNQLGTG MVPLFSKEGH ELAVDKGDIV RFLEFMHVHK
LDVPFIAMYR KEECRSLFKD PEPQDDKDDK KNPDEKPTLR WHKLLWAILE LDRKWLLLQK
RKSALQVYYN KRFEEERSVY DETRLHLNQK LFDSITKSLK VAESEREIDD VDSKFNLHFP
PGDVGVDEGQ FKRPKRKSQY SICSKSGLWE VATKFGYSSE EFGLLISLEE MRTDELEDAK
ETPEEVASRF TCAMFENPQA VLRGARHMAA VEISCEPCVR RHVRSIFMDN AVVSTNPTAD
GNVSIDTHHQ FAGIKWLKDK PLTKFDDAQW LLIQKAEEEK LIQVSVKLPT SIHDQLINDA
HNYYLSDGVS KSAQLWNEQR KQIINDAFDG LLLPSMAKEA RALLTSRAKN WLLTEYGQNL
WDKVSVAPYQ KKDHDVNSSD DYEAAPRVMA CCWGPGKPTT TFVMLDSYGE VLDVLYAGSI
SIRGQNANDQ QRKKNDQQRL LKFMTDHKPH VAVLGAVNLL CPKLKEDIYE IVFKMVEDHP
RDVGQEMDSL QVVYADETLP HLYENSRISS EQLQPQSGIV RRAVALGRYL QNPLAMAATL
CGPAKEILSW KLTPLESFLT PDEKYSMVEQ IMVDATNQVG LDVNLAISHE WLFAPLQFIS
GLGPRKAASL QRSLVRASSI YTRKDLLNHG LGKKVFVNAV GFLRVRRSGN AASSSQFIDL
LDDTRIHPES YGLAQELAKD IYTEDGQGDV NDEDMLEMAI EHVRENPYLL KNLEVDEYAR
SKKRENKKET LNHTRLELIQ GFQDWRKPFV EPNADEEFYM LTGETEQTLS EGKIVQATVR
RVQPQRAVCV LDSGLTGLLN KEDYSDDRRD NDLTEKLDEG DILTCKIKSV VKGRCQVFLS
CKESDLRSDR SRNNKAMDPY YYEDRDNLDN EKEKARKAKE LAKKHFKSRM IVHPRFQNIT
ADEAMEMLSD KEPGESIIRP SSRGPSYLTL TLKIYDGVYA HKDIIEGGKE NKDITSMLRL
GKTLKIGDDV FEDLDEVMDR YVDPLVANLK TMLAYRKFRD GGKAEVDESL RKEKNENPSR
IVYSFGISFE HPGTIILTYI RSSNPHHEYV GLYPKGFKFR KKMFEEIDRL VAYFQRHIDD
PLDAGPSIRS VAAMVPMRSP ATGGSGGWGG SNDGGWRGSS GDRERTSTPS SRTGRNDYRN
GGNHDGHPSG LPRPYGGGGG RRPGRGGRGS YNNRDAERGN GRSPGSVGSG GGGSKRSSMQ
SQTGGSSAGW GSGW
//
