ID A0A251US43_HELAN Unreviewed; 236 AA.
AC A0A251US43;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
GN ORFNames=HannXRQ_Chr05g0155571 {ECO:0000313|EMBL:OTG26158.1},
GN HanXRQr2_Chr05g0230071 {ECO:0000313|EMBL:KAF5807127.1};
OS Helianthus annuus (Common sunflower).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Helianthus.
OX NCBI_TaxID=4232 {ECO:0000313|EMBL:OTG26158.1, ECO:0000313|Proteomes:UP000215914};
RN [1] {ECO:0000313|EMBL:KAF5807127.1, ECO:0000313|Proteomes:UP000215914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. SF193 {ECO:0000313|Proteomes:UP000215914};
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5807127.1};
RX PubMed=28538728; DOI=10.1038/nature22380;
RA Badouin H., Gouzy J., Grassa C.J., Murat F., Staton S.E., Cottret L.,
RA Lelandais-Briere C., Owens G.L., Carrere S., Mayjonade B., Legrand L.,
RA Gill N., Kane N.C., Bowers J.E., Hubner S., Bellec A., Berard A.,
RA Berges H., Blanchet N., Boniface M.C., Brunel D., Catrice O., Chaidir N.,
RA Claudel C., Donnadieu C., Faraut T., Fievet G., Helmstetter N., King M.,
RA Knapp S.J., Lai Z., Le Paslier M.C., Lippi Y., Lorenzon L., Mandel J.R.,
RA Marage G., Marchand G., Marquand E., Bret-Mestries E., Morien E.,
RA Nambeesan S., Nguyen T., Pegot-Espagnet P., Pouilly N., Raftis F.,
RA Sallet E., Schiex T., Thomas J., Vandecasteele C., Vares D., Vear F.,
RA Vautrin S., Crespi M., Mangin B., Burke J.M., Salse J., Munos S.,
RA Vincourt P., Rieseberg L.H., Langlade N.B.;
RT "The sunflower genome provides insights into oil metabolism, flowering and
RT Asterid evolution.";
RL Nature 546:148-152(2017).
RN [2] {ECO:0000313|EMBL:OTG26158.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Leaves {ECO:0000313|EMBL:OTG26158.1};
RA Langlade N., Munos S.;
RT "Sunflower complete genome.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAF5807127.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5807127.1};
RA Gouzy J., Langlade N., Munos S.;
RT "Helianthus annuus Genome sequencing and assembly Release 2.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000256|RuleBase:RU910715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU910715};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU910715}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR EMBL; MNCJ02000320; KAF5807127.1; -; Genomic_DNA.
DR EMBL; CM007894; OTG26158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251US43; -.
DR EnsemblPlants; mRNA:HanXRQr2_Chr05g0230071; mRNA:HanXRQr2_Chr05g0230071; HanXRQr2_Chr05g0230071.
DR Gramene; mRNA:HanXRQr2_Chr05g0230071; mRNA:HanXRQr2_Chr05g0230071; HanXRQr2_Chr05g0230071.
DR InParanoid; A0A251US43; -.
DR OMA; NNTRWKI; -.
DR Proteomes; UP000215914; Chromosome 5.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791:SF178; BIDIRECTIONAL SUGAR TRANSPORTER SWEET; 1.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW Reference proteome {ECO:0000313|Proteomes:UP000215914};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU910715};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
SQ SEQUENCE 236 AA; 26244 MW; B15EA19EF5688468 CRC64;
MDHDQIRLIV GIIGNAIALY LFLSPTPTFL KIVKLKSVQA YKPDTYLATL MNCSMWLFYG
LPIVHPHSLL VVTINSAGIL ITLTFCSIFF IYSSWTCRRK MIIVLILEAI VIAAMVTVTL
TLSHTHPARS MLVGILCLVF NIIMYASPLT IMKTVIRTKS VKYMPVCISI GNLLNGSIWV
VYAALEFDPF IMIPNAVGAV SGMIQIGLYV KYYKTTNWSD DQSPNEIEMP PSASNA
//
