ID A0A251WE10_9CYAN Unreviewed; 337 AA.
AC A0A251WE10;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000256|HAMAP-Rule:MF_01391};
GN ORFNames=B0A82_14730 {ECO:0000313|EMBL:OUC13881.1};
OS Alkalinema sp. CACIAM 70d.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae;
OC Alkalinema.
OX NCBI_TaxID=1934309 {ECO:0000313|EMBL:OUC13881.1, ECO:0000313|Proteomes:UP000194922};
RN [1] {ECO:0000313|EMBL:OUC13881.1, ECO:0000313|Proteomes:UP000194922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CACIAM 70d {ECO:0000313|EMBL:OUC13881.1};
RA Lima A.R., Siqueira A.S., Pereira J.S., Goncalves E.C.;
RT "Draft genome of Alkalinema sp. CACIAM 70d.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with Ccs1. {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000256|HAMAP-
CC Rule:MF_01391}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01391}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|HAMAP-Rule:MF_01391}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OUC13881.1}.
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DR EMBL; MUGG01000123; OUC13881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A251WE10; -.
DR STRING; 1934309.B0A82_14730; -.
DR Proteomes; UP000194922; Unassembled WGS sequence.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR03144; cytochr_II_ccsB; 1.
DR PANTHER; PTHR30071:SF1; CYTOCHROME B_B6 PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748,
KW ECO:0000256|HAMAP-Rule:MF_01391};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01391};
KW Reference proteome {ECO:0000313|Proteomes:UP000194922};
KW Thylakoid {ECO:0000256|HAMAP-Rule:MF_01391};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01391};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01391}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 36..58
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 135..163
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 241..264
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 279..294
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT TRANSMEM 306..327
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01391"
FT DOMAIN 68..331
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
FT REGION 187..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 337 AA; 36131 MW; DC62BEA974314B9F CRC64;
MDLVALQGLL DNASFAVLFV TMLVYWVGAA FPGIPLLSVL GTTGMAISNL TMAALLAARW
LEAGYFPLSN LYESLFFLAW GITTMHLIAE NMSKSRLVGV ATAPVAMGIT AFAALSLSDD
MQASAPLVPA LKSNWLMMHV SVMMFSYATL MVGSVLAIAF LLLTRGQNIE LRGSSVGTGA
YRLTRSQSPA EPSVTASSFS TVSDRSQTGT GGTAVLESPI AATVTALSPQ RLSLADTLDN
ISYRIIGLGF PLLTIGIISG AVWANEAWGS YWSWDPKETW ALITWLVFAA YLHARITKGW
QGRRPALLAA MGFVVVWVCY LGVNLLGKGL HSYGWFL
//
