ID   A0A252BPA5_9PROT        Unreviewed;       492 AA.
AC   A0A252BPA5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=NADH-ubiquinone oxidoreductase subunit 6 {ECO:0000313|EMBL:OUJ08682.1};
GN   ORFNames=HK24_09375 {ECO:0000313|EMBL:OUJ08682.1};
OS   Gluconobacter sp. DsW_058.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Gluconobacter.
OX   NCBI_TaxID=1511210 {ECO:0000313|EMBL:OUJ08682.1, ECO:0000313|Proteomes:UP000194786};
RN   [1] {ECO:0000313|Proteomes:UP000194786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Winans N.J., Newell P.D., Douglas A.E.;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUJ08682.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JOPH01000005; OUJ08682.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A252BPA5; -.
DR   Proteomes; UP000194786; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR023027; Mannitol_DH_CS.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000194786};
KW   Ubiquinone {ECO:0000313|EMBL:OUJ08682.1}.
FT   DOMAIN          28..192
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          221..461
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   492 AA;  54399 MW;  3D76FB37FFFF3454 CRC64;
     MKLTPETLAH LPETILTSPY DRQKVTAGIA HLSVGNFHRA HQAVYTDRTL ALPGQESWGI
     VGLGLMDVPS EVQKAEALQS QGGLYTLREC PSGRPDVVRV VKSLVEYIHA PADRLAALKR
     LTDPAIRIVT MTITEGGYYM DEAGHFMADH PTIVADLKRE VPETAFGILT EALRLRREAG
     VNAFTILSCD NVPSNGEVAR HAVLSFARLR DDELADWISR NVSFPACMVD RITPAVGPAD
     IARLNSESGI EDRAPLFCED FIQWVVEDNF PEGRPAWEQA GVLFTNNVEP YEQVKLRMLN
     ASHSMLALPA VLMGYRFVSE AMEDENLFRL LQQFLGFDSE PHLTAPPGIS LPEYGALLLQ
     RFRNKAVSDQ LLRIASDSTS KLPVFIRPTA EIVVKDNGDM RRIAFLLACY CAYMNGRDDT
     NADFPVTEPR LSKEDRALVT DTDPARALDM GVFAGWGLTD NPAFVQLFTD MRQSLQDRGT
     AATLADVITP KG
//