ID   A0A252C0E4_9PROT        Unreviewed;       336 AA.
AC   A0A252C0E4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:OUJ14668.1};
GN   ORFNames=HK28_12115 {ECO:0000313|EMBL:OUJ14668.1};
OS   Acetobacter sp. DsW_063.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acetobacter.
OX   NCBI_TaxID=1514894 {ECO:0000313|EMBL:OUJ14668.1, ECO:0000313|Proteomes:UP000195092};
RN   [1] {ECO:0000313|Proteomes:UP000195092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Winans N.J., Newell P.D., Douglas A.E.;
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OUJ14668.1}.
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DR   EMBL; JOPL01000041; OUJ14668.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A252C0E4; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000195092; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          241..335
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   336 AA;  36624 MW;  E8C41B748D190090 CRC64;
     MSATQDATAT PANATSSSGA LAPVTVLTGF LGAGKTTLLN HILTAQHGRN YAVIINEFGE
     LGVDNDLVVD ADEEVFEMNN GCICCTVRGD LIRILGSLMK RRQKFDGIIV ETTGLADPAP
     VAQTFFVDAD VRAKTRLDAV VTVVDAYNVL QTLEESPEAT NQIAFADVII LNKVDLVDAA
     KIAEIEARIR TINAFVRIHH ATRGDVALTD VLDQGGFDLQ RALAAHPDFL ENSEHSHEEN
     VTSMSFTLPG PADEPRFQAW IGALLQEQGA DILRAKGILD FKGRDERFAF QAVHMMADGD
     FIGPWRAGEK RESRLVLIGR NLNRPRLRRG FESCLA
//