ID A0A254Q023_9BURK Unreviewed; 692 AA.
AC A0A254Q023;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=CBI30_05380 {ECO:0000313|EMBL:OWS71884.1};
OS Polynucleobacter aenigmaticus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Polynucleobacter.
OX NCBI_TaxID=1743164 {ECO:0000313|EMBL:OWS71884.1, ECO:0000313|Proteomes:UP000198104};
RN [1] {ECO:0000313|EMBL:OWS71884.1, ECO:0000313|Proteomes:UP000198104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MWH-K35W1 {ECO:0000313|EMBL:OWS71884.1,
RC ECO:0000313|Proteomes:UP000198104};
RA Hahn M.W.;
RT "Polynucleobacter sp. MWH-K35W1 isolated from the permanently anoxic
RT monimolimnion of a meromictic lake.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWS71884.1}.
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DR EMBL; NGUO01000008; OWS71884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A254Q023; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000198104; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OWS71884.1};
KW Cilium {ECO:0000313|EMBL:OWS71884.1};
KW Flagellum {ECO:0000313|EMBL:OWS71884.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 17..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 67..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 119..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 205..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 247..269
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 290..319
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 692 AA; 74403 MW; DDC45700E9670BA4 CRC64;
MSNIAFSAWT EKLNTKLLAG PLIIVLLLSM MILPLPAIAL DILFTFNIAL SIMVLLIGLQ
TSKPLDFLAF PTVLLVTTLL RLSLNVASTR VVLTEGHNGP DAAGKVIEAF GHVLIGGNYT
VGIVVFIILT IVNFTVITKG AGRIAEVGAR FTLDAMPGKQ MAIDADLNAG LIGEDDARKR
RTEVGQEAEF YGAMDGASKY VRGDAIAGIL VIIINILGGL IVGVVQHNLS FTEAVKNYTL
LAIGDGLVAQ IPSLIISVAA GVVVSRVGNS QDLGTQLTKQ LFSNPKVLKA TAVILGGMGL
IPGMPHLAFI LLAALLYGIS YLTEKQERKM AIASDITMTE PAPEGKEATW SDVVPVDILG
LEVGFRLVPL VDINQGGDLL KRIKALRKKF AQDVGFLTSA VHICDNLELK PNAYSIKLKG
VELASGESFN GQFLAINPGF VQGQLPGPVT TDPAFGLPAT WIDNKMREQA QSMGYTVVDA
STVIATHLNH VIGMNASELL GRQEVQQLMD MLAKESPKLA EDFIPKMLPL GTLQKVLQNL
LVEGVPIRDM RTIVEALSEN AHQIQDATEL TSKVRIRLGR AIVQQLFPNT NEMSVISLDN
GLERLLMQAM QNNNEGSSIE PGLAQTLARQ AEQASRLQEQ MGFTPVLLVA APLRTTLAKF
LRRVIPNLRV LSHEELPDSK TIRVTNLIGG AA
//
