ID   A0A254Q9P9_9BURK        Unreviewed;       969 AA.
AC   A0A254Q9P9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=FAD-binding oxidoreductase {ECO:0000313|EMBL:OWS72242.1};
GN   ORFNames=CBI30_03370 {ECO:0000313|EMBL:OWS72242.1};
OS   Polynucleobacter aenigmaticus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Polynucleobacter.
OX   NCBI_TaxID=1743164 {ECO:0000313|EMBL:OWS72242.1, ECO:0000313|Proteomes:UP000198104};
RN   [1] {ECO:0000313|EMBL:OWS72242.1, ECO:0000313|Proteomes:UP000198104}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MWH-K35W1 {ECO:0000313|EMBL:OWS72242.1,
RC   ECO:0000313|Proteomes:UP000198104};
RA   Hahn M.W.;
RT   "Polynucleobacter sp. MWH-K35W1 isolated from the permanently anoxic
RT   monimolimnion of a meromictic lake.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWS72242.1}.
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DR   EMBL; NGUO01000004; OWS72242.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A254Q9P9; -.
DR   OrthoDB; 9811557at2; -.
DR   Proteomes; UP000198104; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022827}.
FT   DOMAIN          39..267
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   969 AA;  106297 MW;  47E710A0B65E4E56 CRC64;
     MGSISQWEQL NVELTAALGS SVHFDTAHQA VYASEASNYR QIPIGVVTPK NTEEFIKGIE
     ICHRNKAPVL MRGAGTSMNG QTVNNAVVFD ISKYCNHILA LDPVAGNALV EPGVICDSLR
     DAAELHGLTF APDPSTHSRC TLGGMVANNS CGAHSVMAGK TLENTEALEI LTYDGERFWV
     GPTSDQELAQ IIAAGGRRGQ IYQDLLTLRD RYADLIRARF PNIKRRVSGY NLDQLLPENG
     FNVAKALVGT EGTCALTLAA KVRLVKSPAK RVVLVLGFED IYVAGDAVPE YQSFNPIAIE
     GLDYKIIRGL QQRNLAKAEI DLLPPGNAWV VVEFGDDTLE GAVAQAEKAQ QYFKARTKGP
     QPSTWLVPDP LVQKRIWSIR ENGASATHLS IDPNSPDPVV GWEDAAVDPA RLGEYLRAFQ
     ALVDSYEYET SLYGHFGDGC IHARITFNLR SAEGVAKFRS FIRDAATLVV AFGGSLTGEH
     GDGQARAEFL PIMFGEELMG AMHEFKRIWD PQNKLNPGKV VHPYRVDENL RMGPEYKVVN
     IKTRLNFLSQ EGNGFQRAVE RCVGMGKCRS EKVGTMCPSY RATKEERFST RGRSRLFWEM
     LQGEVIKDGW ESNELKEALD TCLSCKGCKS DCPAHVDMAS YKAEFLSHYH ETNSRPRQAL
     TMGRIGDWAP LASKFSWLIN GVMQTPVLSS IAKWVGGVAQ ERSLPKFASQ SFRKQFKQST
     NASVGQKKVI LWVDTFCEHF HPEVANAAVE VLAHAGFEAT LPKTPLCCGR PLYDFGYLDL
     AKQKLEKILD AIGDQIGAGD DSPIAVVGLE PGCMSVFKDE LLKFFPHDPR AKLLSSSSYL
     LGDFLHEQGY VPPPLDCNVL VHSHCHQKSL FGTKGDVALL SALGAKADYI DSGCCGMAGS
     FGFNPEHVEL SKAVGELVLL PAIRSADQET IILTNGFSCR EQIEQETGRK VKHLAELLQM
     AHQQAAKAS
//