ID A0A254R3T3_9RHOB Unreviewed; 344 AA.
AC A0A254R3T3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=ATO6_15805 {ECO:0000313|EMBL:OWU83881.1};
OS Oceanicola sp. 22II-s10i.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Oceanicola.
OX NCBI_TaxID=1317116 {ECO:0000313|EMBL:OWU83881.1, ECO:0000313|Proteomes:UP000197567};
RN [1] {ECO:0000313|EMBL:OWU83881.1, ECO:0000313|Proteomes:UP000197567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=22II-s10i {ECO:0000313|EMBL:OWU83881.1,
RC ECO:0000313|Proteomes:UP000197567};
RA Lai Q., Li G., Shao Z.;
RT "Oceanicola sp. 22II-s10i Genome Sequencing.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWU83881.1}.
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DR EMBL; AQQU01000006; OWU83881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A254R3T3; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000197567; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000197567}.
FT DOMAIN 14..333
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 344 AA; 37276 MW; E51067B14CF57933 CRC64;
MTDDILIRIA GRAGRITLNR PKALNALTYD MANAIEAALD DWAGNDSVAL VVIDAAGDRA
FCSGGDIEEL YNRGRAGDFD YGRTFWRDEY RLNLKMAEYP KPIVTLMQGY VMGGGVGVGC
HASHRVVGDS SQIAMPECGI GLVPDVGGSL MLARAPGRLG EYLGLTAARM GAGDAIRAGF
ADHYLPEGEW PALTAEMERT GDIAAVERAA VTAPAAALAE HQEVIDRLFT SGDLPSIAVS
SDAEWDEFAK GVRKALLRNS PLAMACTLRM LANLRKEAGG MREALSQEYR YVYRAMEHGD
FLEGIRAQII DRDRNPRWKH ALTSVPDADV ARMLAPLGDD ELTF
//
