ID   A0A254RA83_9RHOB        Unreviewed;       290 AA.
AC   A0A254RA83;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Oxidoreductase {ECO:0000313|EMBL:OWU83592.1};
GN   ORFNames=ATO6_17125 {ECO:0000313|EMBL:OWU83592.1};
OS   Oceanicola sp. 22II-s10i.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Oceanicola.
OX   NCBI_TaxID=1317116 {ECO:0000313|EMBL:OWU83592.1, ECO:0000313|Proteomes:UP000197567};
RN   [1] {ECO:0000313|EMBL:OWU83592.1, ECO:0000313|Proteomes:UP000197567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=22II-s10i {ECO:0000313|EMBL:OWU83592.1,
RC   ECO:0000313|Proteomes:UP000197567};
RA   Lai Q., Li G., Shao Z.;
RT   "Oceanicola sp. 22II-s10i Genome Sequencing.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIBADH-related family.
CC       {ECO:0000256|ARBA:ARBA00009080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWU83592.1}.
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DR   EMBL; AQQU01000007; OWU83592.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A254RA83; -.
DR   OrthoDB; 9812907at2; -.
DR   Proteomes; UP000197567; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR029154; HIBADH-like_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE   3: Inferred from homology;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197567}.
FT   DOMAIN          3..160
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          166..284
FT                   /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF14833"
FT   ACT_SITE        172
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ   SEQUENCE   290 AA;  30254 MW;  FD8544DB0FAF78D7 CRC64;
     MAKVAFIGLG VMGYPMAGHL AAKGHDVTVY NRTGAKAEKW ASEHGGKAAP TPREAAEGAD
     FVMTCVGNDD DLRSVCLGED GAFAGMKAGA ILVDHTTVSA KVTRELYAAA KDGGFGFVDA
     PISGGQAGAE NGALSVMCGG DQSEYDAAEP VIDAYAKICR RLGDSGAGQM TKMCNQIAIA
     GLVQGLAESL HFAQKAGLDG AAVVEVISQG AAGSWQMQNR YKTMLADEFN HGFAVDWMRK
     DLGICLATGN EIEASLPVTA LVDQFYKDVQ KMGGGRWDTS SLFKRLTDAG
//