ID   A0A254SVP6_9BACT        Unreviewed;       387 AA.
AC   A0A254SVP6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Mechanosensitive ion channel protein MscS {ECO:0000313|EMBL:OWV23989.1};
GN   ORFNames=B7982_06070 {ECO:0000313|EMBL:OWV23989.1};
OS   Fibrobacter sp. UWB2.
OC   Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC   Fibrobacter.
OX   NCBI_TaxID=1964358 {ECO:0000313|EMBL:OWV23989.1, ECO:0000313|Proteomes:UP000197741};
RN   [1] {ECO:0000313|EMBL:OWV23989.1, ECO:0000313|Proteomes:UP000197741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWB2 {ECO:0000313|EMBL:OWV23989.1,
RC   ECO:0000313|Proteomes:UP000197741};
RA   Neumann A.P., Suen G.;
RT   "Draft genomes of novel Fibrobacter strains.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWV23989.1}.
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DR   EMBL; MWQK01000002; OWV23989.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A254SVP6; -.
DR   OrthoDB; 9775207at2; -.
DR   Proteomes; UP000197741; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   InterPro; IPR030192; YbdG.
DR   PANTHER; PTHR30414:SF0; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG; 1.
DR   PANTHER; PTHR30414; UNCHARACTERIZED; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          166..234
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
SQ   SEQUENCE   387 AA;  44070 MW;  EEBC7049386C3FEA CRC64;
     MNDYYQFAIL SAVVLAVYAF LYFVVHPLAK WIAIKTPNKF DDLLVKKKVI SRALFFVPVI
     ILVQSFPYVI AKEHWLYDFC EHIGNILFTV AAFLLASAVL DVIESLNERN VKMKLRPMRG
     IFQAIKLAMF CVATILVASQ IVNKSPVIIL STLGAMATVL LLVFRDSILG LVSGIQINLS
     DLLRKGDWIE IERHHADGSV IDITLTSVKV RNWDNTVSVI PAYDLITNSF RNWRGMQESG
     GRRIKRSLFI DQQSIRFLTP EEIEKFMKID VLRPYLEQKL DEIGENSGVS ENVTVTKLNG
     RHLTNIGTFR AYCTAYLRSR KTIAQDMTLM TRQLAPTPTG LPLEIYAFAN TVEWIEYENI
     QSDIFDFLIA SLPEFGLSLY QYANRVP
//