ID   A0A255DQ44_9MYCO        Unreviewed;       352 AA.
AC   A0A255DQ44;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Type III polyketide synthase {ECO:0000313|EMBL:OYN79355.1};
GN   ORFNames=CG716_13025 {ECO:0000313|EMBL:OYN79355.1};
OS   Mycolicibacterium sphagni.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1786 {ECO:0000313|EMBL:OYN79355.1, ECO:0000313|Proteomes:UP000216063};
RN   [1] {ECO:0000313|EMBL:OYN79355.1, ECO:0000313|Proteomes:UP000216063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33027 {ECO:0000313|EMBL:OYN79355.1,
RC   ECO:0000313|Proteomes:UP000216063};
RA   Tortoli E., Trovato A., Cirillo D.M.;
RT   "The new phylogeny of genus Mycobacterium.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005194}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYN79355.1}.
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DR   EMBL; NOZR01000009; OYN79355.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A255DQ44; -.
DR   OrthoDB; 9786288at2; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000216063; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
KW   Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT   DOMAIN          10..196
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          219..350
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        138
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   352 AA;  37318 MW;  5204423BB89BB34A CRC64;
     MSVIAGVRGE LPPHRFSQAE ITEAFLTIGG YGEYEEILRS LHRSAKVDNR HFVMPLDEYP
     ALKDFGQAND LFIEHAVELG SAAIAGALDE AGLRPEDVDL VISTTVTGVA APSLEARIAG
     RLGMRPDVRR VPMFGLGCVA GAAGVARLHD YLRGDPDGVA VLVSVELCSM TYTANKPTMP
     GLVGSALFAD GAGAVVAVGE RRAKKINASG PDIIDSRSHL YPDSLRTMGW DVGASGLELV
     LSADLPDVIE RYLPADVTEF LGAHGLSIDD IGTWVCHPGG PKIIEAIVGS LELPEEALEL
     TWRSLADIGN ISSSSVLHVL RDTIAKHPAA GPSVMMAMGP GFCSELVLLR WH
//