ID A0A255EM61_9ACTN Unreviewed; 868 AA.
AC A0A255EM61;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=ATP-dependent helicase HrpB {ECO:0000313|EMBL:OYN92628.1};
GN Name=hrpB {ECO:0000313|EMBL:OYN92628.1};
GN ORFNames=CGZ91_03910 {ECO:0000313|EMBL:OYN92628.1};
OS Parenemella sanctibonifatiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Parenemella.
OX NCBI_TaxID=2016505 {ECO:0000313|EMBL:OYN92628.1, ECO:0000313|Proteomes:UP000216300};
RN [1] {ECO:0000313|EMBL:OYN92628.1, ECO:0000313|Proteomes:UP000216300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NML 150081 {ECO:0000313|EMBL:OYN92628.1,
RC ECO:0000313|Proteomes:UP000216300};
RA Bernier A.-M., Bernard K., Domingo M.-C.;
RT "Draft whole genome sequences of clinical Proprionibacteriaceae strains.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYN92628.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NMVJ01000001; OYN92628.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A255EM61; -.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000216300; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17990; DEXHc_HrpB; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010225; HrpB.
DR InterPro; IPR049614; HrpB_DEXH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013689; RNA_helicase_ATP-dep_HrpB_C.
DR NCBIfam; TIGR01970; DEAH_box_HrpB; 1.
DR PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08482; HrpB_C; 1.
DR PIRSF; PIRSF005496; ATP_hel_hrpB; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OYN92628.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000216300}.
FT DOMAIN 72..232
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 262..424
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 92853 MW; 1AF8A532D366E1DD CRC64;
MPRSKLGRDI RSSDRRWCSP TTGRTTSPRR RPSDGRRSPS WLTDRWQTGR MPFDLAAIGA
GLPVREALPG LTAALADGGV AVVHAPPGTG KTTLVPPALA NLVDGKVVVT QPRRIAARAG
ARRLAQLSAT TLGDEVGFVV RGDQAVSART RVEFCTAGVL LRRLLTAPDL EGIDAVVLDE
VHERAIETDL AFAMVAELRE LRPDLALVVM SATLDATRWA DLLGGAPVLS VAADLHPLVI
RWAPGPQRLD QRGLTRPFLD HLAGQAVAAL AETDSAVLVF APGARECDEV ADRVRTHGVP
VQVLHGSLAP AAQNEVLARS DPRVIVATSL AESALTVPGV RAVVDSGLAR EPRHDAGRAM
TGLVTVSEAR SSAEQRSGRA ARLGPGLAVR CFPESDWVGM RPFTTPEILT ADLTQTALDL
AVWGAPRGVG LALPDAPNPA AMEAATQTLR SLAALDEDEQ PTVLGRRLAG LPVEPRLGRA
LLETAASVGT RQAAEVVALL SSDVRPAGAD LVGAWRAPAS RQLQVESTRL TRLVDHHPRP
TGLEDDELVA TVVTAAFPDR IARRRRDGDD YLLASGTAGS LPPKSRLHGQ QWLAVAQIGR
VGERAVIRAA VPLTEVAATD LGSALLSEAS QATWSGGRVT ARSTVRLGVI ELSSTPVQPT
ADQGREAARR ALADRGLPEV LGWGEEVERL RRRLALLRDQ LGEPWPQVDD EALVQRAEEW
LGPELGDLAR GVAASRIDLV AALRRLLPWP AASQFDTLAP ERLQVPTGSR IRLDYPELPT
ERVVLPVKLQ ECFGLLDTPR IVDGRVPVLL HLLSPAGRPL AVTDDLASFW VNAYPAVRAE
NRGRYSKHPW PEDPLTAPPR KGTSRSGR
//
