ID A0A255HRN8_9BURK Unreviewed; 521 AA.
AC A0A255HRN8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=3-hydroxyacyl-CoA dehydrogenase PaaC {ECO:0000313|EMBL:OYO30950.1};
GN Name=paaC {ECO:0000313|EMBL:OYO30950.1};
GN ORFNames=CD932_07285 {ECO:0000313|EMBL:OYO30950.1};
OS Janthinobacterium sp. PC23-8.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=2012679 {ECO:0000313|EMBL:OYO30950.1, ECO:0000313|Proteomes:UP000216749};
RN [1] {ECO:0000313|EMBL:OYO30950.1, ECO:0000313|Proteomes:UP000216749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC23-8 {ECO:0000313|EMBL:OYO30950.1,
RC ECO:0000313|Proteomes:UP000216749};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC {ECO:0000256|ARBA:ARBA00005086}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYO30950.1}.
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DR EMBL; NJGY01000001; OYO30950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A255HRN8; -.
DR OrthoDB; 5287258at2; -.
DR Proteomes; UP000216749; Unassembled WGS sequence.
DR GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:InterPro.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:0010124; P:phenylacetate catabolic process; IEA:InterPro.
DR Gene3D; 1.10.1040.50; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR011967; 3-OHacyl-CoA_DH_PaaH.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR041040; 3HCDH_RFF.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR02279; PaaC-3OHAcCoADH; 1.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR Pfam; PF18321; 3HCDH_RFF; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 10..187
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 190..287
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 363..432
FT /note="3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-
FT fold"
FT /evidence="ECO:0000259|Pfam:PF18321"
FT DOMAIN 433..517
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 521 AA; 55051 MW; 3C8FA0E5E56961B4 CRC64;
MAALDNNSIV AVIGSGAMGA GIAQVAAAAG YRVKLYDTRP EAVSKALADI GKMYVKLAEK
GRMTAQQAQD ASARLQGAAS LQDASDAALV VEAIVENLDV KRSLFADLEA LVDDDCILAT
NTSSISVTAI AAKLRHPERL VGMHFFNPVP LMALVEVVSG LATSDEVATT VHDTALAWGK
QPVHAKSTPG FIVNRVARPF YAEGWRLLNE QAGDAATIDA VLREAGGFRM GPFELMDLIG
HDVNFSVTQS VFGAYFNDPR FTPSVLQQEM VNAGFLGRKS GRGFYRYGEG ASIPDAQQES
TQPRPEVVAL SSAVGGDGRG HSGIVHALVR RLEAAGINLT SRVTLEGQVS DTAPALHCNG
AAIYLTDGRS ATQRAHDNNH ADTVLFDLAL DYASAKRVAL ARADQCGDEA YNAAVGLFQA
AGFTVTRLDD VPGLAVMRTV AMLANEAADA VHQGVCTAAA VDIAMQKGVN YPRGPLAWAD
AVGVQHIVAV LHHLAQGYGE DRYRVSPLLR RKLANGALFH A
//
