ID A0A255SIB5_9BACT Unreviewed; 754 AA.
AC A0A255SIB5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:OYP52683.1};
GN ORFNames=CIK97_00230 {ECO:0000313|EMBL:OYP52683.1};
OS Prevotella sp. P3-120.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=2024220 {ECO:0000313|EMBL:OYP52683.1, ECO:0000313|Proteomes:UP000216094};
RN [1] {ECO:0000313|EMBL:OYP52683.1, ECO:0000313|Proteomes:UP000216094}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P3-120 {ECO:0000313|EMBL:OYP52683.1,
RC ECO:0000313|Proteomes:UP000216094};
RA Accetto T., Nograsek B., Avgustin G.;
RT "Comparative genomics of non-oral Prevotella species.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYP52683.1}.
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DR EMBL; NPJD01000001; OYP52683.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A255SIB5; -.
DR Proteomes; UP000216094; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:OYP52683.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:OYP52683.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:OYP52683.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216094}.
FT DOMAIN 216..360
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 497..650
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 664..753
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 144..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..170
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 84455 MW; E6EDCED4EC58A3CA CRC64;
MNRAIQQACE LAHRSSHEFL MPEHVLLALC QIAPSFVNVL KQSLDCQPGE LAEDVEKWLA
SQEKAPKPVD LELSSSMRRI FTICKGENAD RVLCVTSFIE AMMRDAECMG TYLLTKHLKV
TEVFLLLSLH EYCDAKDSYV AEEELDDDLD DLEDDDLDDD DLEDDDEMMG SPSDFASSSD
WKQWTTDITA EATDHLPIIG REAELDRTIE VLCRMEKNNP LHIGEPGVGK TALIYGLAQR
IAKGHVPYRL QKAHIYSIEM GQLMAGAQFR GEFEKRLKDV LDGATAQGNS VIYLDEIHLM
MGGEQAQSDS ISAFDVMKPY LDRGKLRFIG STTYEAFNRT LAKSKAVTRR FQQIDIKEPS
VEDTLRIVEA LLPTFQNYHN VIYRKDAWTY AVESSARLIT NRQLPDKAID IIDEAGAYLE
VHPRNRLHNY VTKSLVDEIL NKVCRIDADA LKEADNNSLK DLVTQMKSQI YGQDKAIERL
TDAVMMAKAG LTDSDKPMAS LLFVGPTGVG KTEVARVLAR QLGVELVRFD MSEYAEKHTV
AKLIGSPAGY VGYDDGGLLT SAIRKTPNCV LLLDEIEKAH SDIYNILLQV MDYARLTDNR
GQQADFHHVI IIMTSNAGAQ YASQASVGFT GHVSRGEAMR QQVKRVFKPE FINRLTDIVT
FRDMDKTMAT LILRKKLALL SDKLGQRQVK LTVSQQAFDR LLTLGFTPEY GAREMDRVIG
NNIKPLLMRA LLFGSLSKGG IATVDCKDGV FVVK
//
