ID   A0A255SVY9_9BACT        Unreviewed;       425 AA.
AC   A0A255SVY9;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0000313|EMBL:OYP57040.1};
DE            EC=2.5.1.49 {ECO:0000313|EMBL:OYP57040.1};
GN   ORFNames=CIK99_08285 {ECO:0000313|EMBL:OYP57040.1};
OS   Prevotella sp. P5-92.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=2024222 {ECO:0000313|EMBL:OYP57040.1, ECO:0000313|Proteomes:UP000216769};
RN   [1] {ECO:0000313|EMBL:OYP57040.1, ECO:0000313|Proteomes:UP000216769}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P5-92 {ECO:0000313|EMBL:OYP57040.1,
RC   ECO:0000313|Proteomes:UP000216769};
RA   Accetto T., Nograsek B., Avgustin G.;
RT   "Comparative genomics of non-oral Prevotella species.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYP57040.1}.
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DR   EMBL; NPJG01000079; OYP57040.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A255SVY9; -.
DR   OrthoDB; 9803729at2; -.
DR   Proteomes; UP000216769; Unassembled WGS sequence.
DR   GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR   PANTHER; PTHR43797:SF3; O-ACETYLHOMOSERINE SULFHYDRYLASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216769};
KW   Transferase {ECO:0000313|EMBL:OYP57040.1}.
FT   MOD_RES         208
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   425 AA;  46166 MW;  665291A98B92D1C2 CRC64;
     MEKNLRQASL CIHSGYEPKN GEPVELPIVQ STTFKYESSD EMAKLFDLER DGYFYTRLAN
     PTNDAVACKI AALEGGIGAV LTSSGQAANF FAVFNICEAG GHIVASNEIY GGTYNLFGVT
     LKKLGIDCTF VSPDATEEEI GQAFRPNTKA LFGETISNPG CKVLDIEKFA RIAHSHGVPL
     VVDNTFATPI NCRPFEWGCD IVTHSTTKYM DGHATQVGGC VVDSGNFDWM AHADKYPGLC
     TSDESYHGLT YAKDFGKKGY ITKIVAQLMR DFGSTPAPQN SFLLNLGLET LAVRMERHCS
     NAQRVAEYLS ADPRVAWVRY SGLPGDSSHA LAIKYMPGGS CGVIAFGLKG SRETAIKFMD
     SLKMINIATH VADLRTCVLH PASHTHRQLS DEQLRAAGIA PEFIRLSVGL EDADDIIDDI
     KQALG
//