ID A0A255T189_9BACT Unreviewed; 933 AA.
AC A0A255T189;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CIL02_13025 {ECO:0000313|EMBL:OYP58880.1};
OS Prevotella sp. P3-122.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=2024223 {ECO:0000313|EMBL:OYP58880.1, ECO:0000313|Proteomes:UP000215645};
RN [1] {ECO:0000313|EMBL:OYP58880.1, ECO:0000313|Proteomes:UP000215645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P3-122 {ECO:0000313|EMBL:OYP58880.1,
RC ECO:0000313|Proteomes:UP000215645};
RA Accetto T., Nograsek B., Avgustin G.;
RT "Comparative genomics of non-oral Prevotella species.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYP58880.1}.
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DR EMBL; NPJH01000080; OYP58880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A255T189; -.
DR OrthoDB; 1116352at2; -.
DR Proteomes; UP000215645; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF13424; TPR_12; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000215645};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 167..200
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 407..618
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 670..785
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 829..930
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT COILED 774..801
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 718
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 933 AA; 104805 MW; 40D6ABA7E567FAB8 CRC64;
MTRMAATKIL QAGLICLTMT NMSCGEEKNS NAAKTHEFTD SLVSLRNRGK DLRDEGRYDE
ALMLHNDGLT LAKSTGDTCE WVQALNNIGT DYRRMGMLDI AQEYHYEAWR MCEESADTCR
TMRKNRVVSL NGLGNIYLTI KDYVRADSAF RQALAGEREL GSATGQAINY ANIGAIYNAQ
GNYKEARRYY EMSLKMNEKD SNTLGLSLCH TYLGNLHEQA KEYDMARQEY MTAYELIKDS
KDKWHTLEPM MALVQLGLDT GNMAEAEAWL KEVDKEMKGL NSREHESEIY TLHYRMDNSK
GLYREALRWY EKAKAMEDSI MDQDKNNRIH NIGISIERRR QEMILARTKS ELKAEKSRST
FWLWGGVILL TVSVLTVGLM TYVQRIKAAS MKALQEASGM REDFFTNITH EFRTPLTVIL
GLSGEMKEKS DNEEWRSKCE AIYRHGNSLL RLVTQLLDIA KIKSRVGEPD WRHGNIVAQV
KMIAETFNDY AASRGIELAV EAQGDIDIDF VPDYINNVVS NLLSNSLKFT PTGGQITIKT
ASDGKLLTLA VTDTGKGMSE EEKNNIFKPF YSSATGNKGT GVGLALVKQI ADSLEGKITV
ESTEGEGSTF TLTIPVRKAV KGVRKLNPAN YDMAQAKTEA MAGLDNGNST EADMQEDLQE
GMQGNQQRKV VLVIEDNRDV AKYIGSQLSA DYDVAYAVNG NDGLKKAISM IPDMIVSDLM
MPEMDGLEMC SKIRSNEEVN HIPVIMLTAK ITEADKLKGL EAGVDAYLPK PFNADELRLR
VAKLLEQRQV LRHKYSQAKA AGKDIKDITV VADDRQAMAT MEMADAFLNK ATDYIYAMLE
RYEVVSVSTL AEKLNMNARQ LHRKLTAVAD ITPNTFIMNL RIRKAMKMIE DNKSIPLKNV
AFDCGFSEYS HFTKSFKSIV GVSPSEYGKE KKI
//
