ID   A0A255TI42_9BACT        Unreviewed;       449 AA.
AC   A0A255TI42;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Sodium:alanine symporter family protein {ECO:0000313|EMBL:OYP64191.1};
GN   ORFNames=CIL02_00305 {ECO:0000313|EMBL:OYP64191.1};
OS   Prevotella sp. P3-122.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=2024223 {ECO:0000313|EMBL:OYP64191.1, ECO:0000313|Proteomes:UP000215645};
RN   [1] {ECO:0000313|EMBL:OYP64191.1, ECO:0000313|Proteomes:UP000215645}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P3-122 {ECO:0000313|EMBL:OYP64191.1,
RC   ECO:0000313|Proteomes:UP000215645};
RA   Accetto T., Nograsek B., Avgustin G.;
RT   "Comparative genomics of non-oral Prevotella species.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYP64191.1}.
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DR   EMBL; NPJH01000002; OYP64191.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A255TI42; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000215645; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215645};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        56..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        144..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        178..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        238..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        304..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        346..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        415..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   449 AA;  48115 MW;  EE1DC1412A83200B CRC64;
     METINDFFAA ASSLLWGWPM IILLLGTHVF LTIRLRCPQL RLLTAIRLSI RRDKDASGDV
     SQFGALATAL AATIGTGNII GVATAIALGG PGAVFWCWLT GVFGMSTKYA EGLLAIKYRQ
     QTTNGNMLGG PMYALEKGLG WKKLAIMFAI FTAIASFGIG NTVQANAIAT IANSTYGISP
     WIMGSIVCAL TAAVILGGVK SIAKVCGMLV PFMALFYVIG CIYILIVNHN YLWPALSLIV
     NSAFSPQAAG GGFVGTSVMM AARYGIARGL FSNESGLGSA PIVAAAAQTR NPVRQALVSS
     TGTFWDTVVI CALTGIVIVS SVIAYPDINY SDGAALTKMA FNKIPYVGAP LLSFGLLTFA
     FSTILGWCYY GDSAVEYLKG KRWTYVYRIL YIAAVFIGSV ASLNIVWNIA DCMNALMAIP
     NLLSLLFLNG VLVHETRKYL WRDRLDKEM
//