ID   A0A255Z5Z1_9PROT        Unreviewed;      1132 AA.
AC   A0A255Z5Z1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=CHU95_03470 {ECO:0000313|EMBL:OYQ36841.1};
OS   Niveispirillum lacus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Azospirillaceae; Niveispirillum.
OX   NCBI_TaxID=1981099 {ECO:0000313|EMBL:OYQ36841.1, ECO:0000313|Proteomes:UP000216998};
RN   [1] {ECO:0000313|EMBL:OYQ36841.1, ECO:0000313|Proteomes:UP000216998}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TH1-14 {ECO:0000313|Proteomes:UP000216998};
RA   Cai H.;
RT   "Niveispirillum cyanobacteriorum sp. nov., isolated from cyanobacterial
RT   aggregates in a eutrophic lake.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYQ36841.1}.
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DR   EMBL; NOXU01000020; OYQ36841.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A255Z5Z1; -.
DR   OrthoDB; 9810135at2; -.
DR   Proteomes; UP000216998; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF23; RECBCD ENZYME SUBUNIT RECB; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Endonuclease {ECO:0000313|EMBL:OYQ36841.1};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000216998}.
FT   DOMAIN          8..475
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          476..781
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         29..36
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1132 AA;  121855 MW;  237DFE683BD30FF1 CRC64;
     MSSVSKMLKD DGARRDAISL HDRSILVEAG AGSGKTAVMA GRIAAMMAEG IAPRSIAAVT
     FTELAASELL SRVREFVADL SAGTIATELR VALPDGLSQA HRNNLAAASA AIDEITCSTI
     HGFCQRLIKP YPAEADIDPG AGVMDRNQAD LTFLEIVDGW LRGRLSGGQG GILAEMVLHS
     PGETVALIHK IAENLRRRPA LSAPPVSSLD AYLTAFRQAT ANFASFMGGT AAAEPETVTI
     VERLAEMATA VANGPDPATP AGLVRLLTAR PHPDLCTKTG AFASYRKKGK WAAAAKQAGF
     SKADGDRLND AAEIHYTACC DAWVALAQAV AGHALAALID EARPILQRYR DHKRASAQLD
     FDDLIFSARN LLRDHDAVRR ALGQRFAHVL VDEFQDTDPL QTEIFWRLCG EPVDVDADWT
     RFQIRPGALF LVGDPKQAIY RFRGADVGAY VQARDAFRAQ HPGSLLSIST NFRSCASILT
     FVNERFEAVL SADGQPGFTA LDPFHDDRGG LCVAALDIAV ADENGKASAE QQRDAEADAI
     AELCVRLIES HPIVDRRSAA ERPCQPGDIA LLAPTGAELW RYEEALERRG IPVATQAGKG
     FFRRQEIQDL LALTRVLADR RDTLALGALL RGPLVGLTEE DLLDIIWGLP RSEEQPDRIP
     RLDLSIDPAV VTHPLARQII ERLQSLSRRG NSTTPHELLS QAVDVMRVRP LLLERHRGQA
     ERALANVDLY LSLSTGYAVR GLRAFAEAMT AAWSDEARAV EGRPDAQEEA VALFTMHAAK
     GLEWPIVIPI NTMTGVMTTD SAVIDRQTET FYCPVLGVTP EGYEIARQAE KEELDRERIR
     LWYVAATRAR ELLVLPRLDV TQSRSAWIGL VDLSLAALPG LDVSHLPTGF AAAGAGAGNT
     QTRDGFAAEA EAIAAAQMRL TWLAPSRDEN AAGTVLREEE AALWTGSADD QPPELEAAAL
     VQGGRERGLI LHKLMEEVLT GETLEVDADL AERADDLIRS LGRSPVADPA AGLSAQELAA
     CVARTLALPD IAALRPGLLA EFPVYSARTA DGVEIATAGI VDALTLTAEG RPAVVVDWKS
     DVVPALEMLD HYRAQVRAYL DMTGAERGLI VLMTSGSVIP ILPTKQTESE AA
//