ID A0A255ZS26_9FLAO Unreviewed; 731 AA.
AC A0A255ZS26;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=recQ {ECO:0000313|EMBL:OYQ44236.1};
GN ORFNames=CHX27_07970 {ECO:0000313|EMBL:OYQ44236.1};
OS Flavobacterium aurantiibacter.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2023067 {ECO:0000313|EMBL:OYQ44236.1, ECO:0000313|Proteomes:UP000216035};
RN [1] {ECO:0000313|EMBL:OYQ44236.1, ECO:0000313|Proteomes:UP000216035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TH167 {ECO:0000313|EMBL:OYQ44236.1,
RC ECO:0000313|Proteomes:UP000216035};
RA Cai H.;
RT "Flavobacterium cyanobacteriorum sp. nov., isolated from cyanobacterial
RT aggregates in a eutrophic lake.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYQ44236.1}.
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DR EMBL; NOXX01000194; OYQ44236.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A255ZS26; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000216035; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048671; RecQ-1-like_HTH.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF21220; RecQ-1-like_HTH; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OYQ44236.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000216035}.
FT DOMAIN 29..200
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 225..378
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 534..614
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 731 AA; 82795 MW; 4049ED8B2F502AF4 CRC64;
MNNKEIDIHN ELKKHFGFDS FKGLQEQVIR SILANQNTFV IMPTGGGKSL CYQLPALVLE
GTAIVVSPLI ALMKNQVDAI RSLSDKEGVA HVLNSSLNKT EINQVKKDIT NGVTKLLYVA
PESLTKEEYV QFLRSVPISF VAIDEAHCIS EWGHDFRPEY RNLRYIIKQL GEVPVIGLTA
TATPKVQEDI LKNLDMTDAK TFKASFNRPN LFYDVRPKTK NVEADIIRFI RQYKGKSGII
YCLSRKKVEA IAQVLQVNGI SAVPYHAGLD AKTRAKHQDM FLMEDVDVVV ATIAFGMGID
KPDVRFVIHH DIPKSLESYY QETGRAGRDG GEGYCLAYYS YKDVEKLEKF MSGKPVAEQE
IGFALLQEVV AYAETSMSRR KFLLHYFGEE FDSENGEGAD MDDNVRNPKS KVEAQDQVVK
LLKVVRDTKH LYKAKEVIYT LIGKVNAVIK AHRTDSQTFF GSGEKHDERY WMALIRQVLV
EGLLTKDIET YGILKVTEKG LDYIDNPTSF MMSEDHEYDE NEDDSIVTAS KSSGTADEAL
MAILRDLRKK VAKKAGVPPF VVFQDPSLED MALKYPTTLE ELSNVHGVGE GKAKKYGKEF
VEMINRYVEE NDIVRPDDLV VKSTGANSAN KLYIIQNIDR KLSLDDIASA KGLTMDALLK
EMEQIVYAGT KLNIKYWIDD ILDEDQQEEI HDYFMESETD RIEDALKEFD GEYDIDELRL
MRIKFISEVA N
//
