ID A0A256H5T9_9EURY Unreviewed; 526 AA.
AC A0A256H5T9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DJ82_09585 {ECO:0000313|EMBL:OYR39412.1};
OS Halorubrum sp. Ib24.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1383850 {ECO:0000313|EMBL:OYR39412.1, ECO:0000313|Proteomes:UP000216554};
RN [1] {ECO:0000313|EMBL:OYR39412.1, ECO:0000313|Proteomes:UP000216554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ib24 {ECO:0000313|EMBL:OYR39412.1,
RC ECO:0000313|Proteomes:UP000216554};
RX PubMed=24782836; DOI=10.3389/fmicb.2014.00140;
RA Fullmer M.S., Soucy S.M., Swithers K.S., Makkay A.M., Wheeler R.,
RA Ventosa A., Gogarten J.P., Papke R.T.;
RT "Population and genomic analysis of the genus Halorubrum.";
RL Front. Microbiol. 5:140-140(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYR39412.1}.
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DR EMBL; NHOX01000037; OYR39412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A256H5T9; -.
DR Proteomes; UP000216554; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OYR39412.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216554};
KW Transferase {ECO:0000313|EMBL:OYR39412.1}.
FT DOMAIN 1..53
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 307..504
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 526 AA; 56525 MW; 7C49499F3B81CA80 CRC64;
MERFPEALGG LPDPVLIVDT DGVVRADNPR VEPVLGYGPA ELEGTDVERL LYDAGGGSAG
AELYGHVADP EPRSMAASLD LTARRRDGTE IPVTISLGPF ERAGEAYLVV TVVDVREERA
RQAELRRRTR TLESLHEATQ DLLKTTDREV AAEAAVEYVE EVLGHPIAGI WLYDESRDAL
EPHVWTDAAD EVVGEHPVFS ADGRSISWQV FDSGKPEYVA DIRTDPDRYN PDSPIRSELV
LPLGRYGVIN VGATESDAFD DSDLAIARIW AATVTMVFVR IERERQLRAR EAEVARERDR
LEEFASLVSH DLRNPLNVAA GNLELIRTRL EGERAVPPEL ETVARSLDRM GALVDDMLTL
AKQGTAIDET EAVSLSALAE ESWANVDTAD AELVLADDLP LRADRSRLRQ AVENLFANAV
AHGGAGVRVE VGALDAAGEP GFYVADDGPG IPDAVRDEAF DAGVSTDEDG TGFGLKIVAE
VADAHGWSVD FVDATGGGAR FEFRGVEAAD AADLPADGGA DGDAGD
//
