ID A0A256H7H0_9EURY Unreviewed; 987 AA.
AC A0A256H7H0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=FAD-binding oxidoreductase {ECO:0000313|EMBL:OYR40046.1};
GN ORFNames=DJ82_08395 {ECO:0000313|EMBL:OYR40046.1};
OS Halorubrum sp. Ib24.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=1383850 {ECO:0000313|EMBL:OYR40046.1, ECO:0000313|Proteomes:UP000216554};
RN [1] {ECO:0000313|EMBL:OYR40046.1, ECO:0000313|Proteomes:UP000216554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ib24 {ECO:0000313|EMBL:OYR40046.1,
RC ECO:0000313|Proteomes:UP000216554};
RX PubMed=24782836; DOI=10.3389/fmicb.2014.00140;
RA Fullmer M.S., Soucy S.M., Swithers K.S., Makkay A.M., Wheeler R.,
RA Ventosa A., Gogarten J.P., Papke R.T.;
RT "Population and genomic analysis of the genus Halorubrum.";
RL Front. Microbiol. 5:140-140(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYR40046.1}.
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DR EMBL; NHOX01000032; OYR40046.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A256H7H0; -.
DR Proteomes; UP000216554; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.30.70.2190; -; 1.
DR Gene3D; 3.30.70.2740; -; 1.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR004017; Cys_rich_dom.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02754; CCG; 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000216554}.
FT DOMAIN 59..291
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT DOMAIN 635..667
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 987 AA; 107313 MW; 34ADAD204EA5A351 CRC64;
MGSKNTTPDP STDPRANYDY QSETEHDSSL VADLDALVDG DVRFDEYSKQ MYATDASAYE
VTPIGVVYPT STADVAAVME YCAAEEIPAL PRGGGTSLAG QSVNEAIVLD FTRYMTDVVD
VDPEGERARA RTGITLGELN RTLEPHGLKF APDPSTADRS ALGGAIGNNT TGAHSLKYGK
TDAYVEEVEA VLADGSVETF GEVSVAELRG AADPDGTTLE RIYAEIVRII DEEADEVDER
YPDLKRNVSG YNLDVLIEEA ESGTVNLARL LVGSEGTLAI VTEAEVSLEP IPETKGVALL
TYHDLLDAME DVGPILEHDA AAVEVLDGVL VDLARELEEF KDVIGLLPDE TDSFLLIEFY
ADDEESAKRQ VDDLIEDRVG DLAFDGMAAY DEETQKKFWK MRKASTPILL SRTGDEKHIA
FIEDLAIPPE HLPEYTKEFK EIFEDHDTFG SFYAHAGPGC MHVRPLINTK NAEGTETMVS
ISDAATDLAV KYGGSVSGEH GDGRARTQWN RKLYGDRLWH VFQDLKTAFD PDWLLNPGSV
CGDHDMSENL RFGEEYEFDA GFEPALEWEN ENGFQGMAEL CHGCGGCRTS QEGAGGVMCP
TYRASQEEIT STRGRANLLR QAMSGDLSED EQFDTEFMRE VLDLCVGCKG CSIDCPSEVD
MAKMKVEVEH AHHEEHGADL RSKLFANVDA LSKLGSATAP LSNLGTKVPG ARVVMEKTLG
IARERSLPTF HRETFVDWWA DRGGSTVSES TADRRVVLVP DTVTNYNNPK AGKAAVRVLE
AAGVHVSVAE EITDSGRPAH SKGLLGKARE TAEANVATLA AHVDDGRDVV VVEPSDAVML
QSDYLDLLSS DAAAQVAEHA YGVLEYLDTR RLDEALDADG GAERLTYHGH CHQKSVKKDH
HAVGVLRRTG FRVDPLDTSC CGMAGTFGYE SEHYSMSQAI GSMLFDRIDD SDGDSVVAPG
ASCRTQIGDE YDEKPPHPIE KIADALA
//
