ID   A0A257AQ23_9ARCH        Unreviewed;       157 AA.
AC   A0A257AQ23;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Transcription elongation factor Spt5 {ECO:0000256|HAMAP-Rule:MF_00950};
GN   Name=spt5 {ECO:0000256|HAMAP-Rule:MF_00950};
GN   ORFNames=B6U74_00520 {ECO:0000313|EMBL:OYT66530.1};
OS   Candidatus Bathyarchaeota archaeon ex4484_205.
OC   Archaea; Candidatus Bathyarchaeota.
OX   NCBI_TaxID=2012510 {ECO:0000313|EMBL:OYT66530.1, ECO:0000313|Proteomes:UP000216556};
RN   [1] {ECO:0000313|Proteomes:UP000216556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Dombrowski N., Seitz K.W., Teske A., Baker B.;
RT   "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT   hydrothermal sediment communities.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stimulates transcription elongation. {ECO:0000256|HAMAP-
CC       Rule:MF_00950}.
CC   -!- SUBUNIT: Heterodimer composed of Spt4 and Spt5. Interacts with RNA
CC       polymerase (RNAP). {ECO:0000256|HAMAP-Rule:MF_00950}.
CC   -!- SIMILARITY: Belongs to the archaeal Spt5 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00950}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYT66530.1}.
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DR   EMBL; NJEE01000002; OYT66530.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257AQ23; -.
DR   Proteomes; UP000216556; Unassembled WGS sequence.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0140673; P:transcription elongation-coupled chromatin remodeling; IEA:InterPro.
DR   CDD; cd06091; KOW_NusG; 1.
DR   CDD; cd09887; NGN_Arch; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR   HAMAP; MF_00950; Spt5_arch; 1.
DR   InterPro; IPR005100; NGN-domain.
DR   InterPro; IPR006645; NGN-like_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR014722; Rib_uL2_dom2.
DR   InterPro; IPR039659; SPT5.
DR   InterPro; IPR011590; Spt5_arc.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   NCBIfam; TIGR00405; KOW_elon_Spt5; 1.
DR   PANTHER; PTHR11125; SUPPRESSOR OF TY 5; 1.
DR   PANTHER; PTHR11125:SF7; TRANSCRIPTION ELONGATION FACTOR SPT5; 1.
DR   Pfam; PF03439; Spt5-NGN; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
PE   3: Inferred from homology;
KW   Elongation factor {ECO:0000313|EMBL:OYT66530.1};
KW   Protein biosynthesis {ECO:0000313|EMBL:OYT66530.1};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW   Rule:MF_00950}; Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00950}.
FT   DOMAIN          6..90
FT                   /note="NusG-like N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00738"
SQ   SEQUENCE   157 AA;  17882 MW;  1ECC726ED5DBF604 CRC64;
     MEEKRKSKVF LVRTTAGQEK NVAELIYAKS LAEELNILSV VAPEGLRGYV FVEAYSPHDV
     DEAIRDVRHA RKRVPGIVDM KDVLQYFEER KIIEELDVGD RVEIIAGIFK HMKARVIAIN
     KPRNEVTIEL EESRSPLPIS IDADNLKIVE KAKKEEG
//