GenomeNet

Database: UniProt
Entry: A0A257CIS2_9BURK
LinkDB: A0A257CIS2_9BURK
Original site: A0A257CIS2_9BURK 
ID   A0A257CIS2_9BURK        Unreviewed;       552 AA.
AC   A0A257CIS2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   16-JAN-2019, entry version 9.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=CFE46_00760 {ECO:0000313|EMBL:OYT88998.1};
OS   Burkholderiales bacterium PBB6.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=2015568 {ECO:0000313|EMBL:OYT88998.1, ECO:0000313|Proteomes:UP000216978};
RN   [1] {ECO:0000313|EMBL:OYT88998.1, ECO:0000313|Proteomes:UP000216978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBB6 {ECO:0000313|EMBL:OYT88998.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L.,
RA   Hubert P., Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M.,
RA   Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom
RT   Asterionella formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OYT88998.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; NKIH01000001; OYT88998.1; -; Genomic_DNA.
DR   Proteomes; UP000216978; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000216978};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216978}.
FT   DOMAIN      249    383       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      460    529       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     257    264       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   552 AA;  59789 MW;  39E314A63D4B07E0 CRC64;
     MSPDLWQRAC ERLAAEMPEQ QFNTWIRPLP PADIASDDGE QGAVASLRVP NRFKLDWIRS
     QYSTRIENVL TELAGVPTRL ELTLAPREAG AVAAPRPMPA RPNSAARVLA GALASVAPAA
     AAAQAAPAAS RPLARSPAAA TAAVPATPPA LSTPDATAPT DTATPIQAPL FEAGSAAAKA
     AALAAAVQAA TPPAPAAPRI VKASTLPTPP VINRHRLNTA LTFDTLVAGR ANQMARTAAL
     HVAGAPGQMY NPLFIYGGVG LGKTHLVHAV GNALLQDNPN AKVLYLHAEQ FITDVVKNYQ
     RKTFDELKAK YHQLDLLLID DVQFFAGKER TQEEFFNAFE ALLAKRAHII MTSDTYPKGL
     VDIDERLTSR FDSGLTVAIE PPELEMRVAI LLSKARAEGT PLPEDVAFFV AKNVRANVRE
     LEGALRKVLA YAKFSHKEIT IHLAREALKD LLSIQNRQIS VENIQKTVAD FYKIKIADMY
     SKKRPASIAR PRQIAMYLAK ELTQKSLPEI GELFGGRDHT TVLHAVRKIG GERQKNTELN
     QQLHVLEQTL KG
//
DBGET integrated database retrieval system