ID A0A257DBG7_9BURK Unreviewed; 488 AA.
AC A0A257DBG7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=mannose-1-phosphate guanylyltransferase {ECO:0000256|ARBA:ARBA00012387};
DE EC=2.7.7.13 {ECO:0000256|ARBA:ARBA00012387};
GN ORFNames=CFE40_09460 {ECO:0000313|EMBL:OYT99002.1};
OS Burkholderiales bacterium PBB1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=2015563 {ECO:0000313|EMBL:OYT99002.1, ECO:0000313|Proteomes:UP000216950};
RN [1] {ECO:0000313|EMBL:OYT99002.1, ECO:0000313|Proteomes:UP000216950}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBB1 {ECO:0000313|EMBL:OYT99002.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-
CC alpha-D-mannose; Xref=Rhea:RHEA:15229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:37565, ChEBI:CHEBI:57527,
CC ChEBI:CHEBI:58409; EC=2.7.7.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001083};
CC -!- SIMILARITY: Belongs to the mannose-6-phosphate isomerase type 2 family.
CC {ECO:0000256|ARBA:ARBA00006115, ECO:0000256|RuleBase:RU004190}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYT99002.1}.
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DR EMBL; NKIN01000003; OYT99002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257DBG7; -.
DR Proteomes; UP000216950; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd02213; cupin_PMI_typeII_C; 1.
DR CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR049577; GMPP_N.
DR InterPro; IPR006375; Man1P_GuaTrfase/Man6P_Isoase.
DR InterPro; IPR001538; Man6P_isomerase-2_C.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR NCBIfam; TIGR01479; GMP_PMI; 1.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF01050; MannoseP_isomer; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Isomerase {ECO:0000313|EMBL:OYT99002.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:OYT99002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216950};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OYT99002.1}.
FT DOMAIN 10..303
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 332..482
FT /note="Mannose-6-phosphate isomerase type II C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01050"
SQ SEQUENCE 488 AA; 53233 MW; 01BBD70D09B9CBCE CRC64;
MSTAPIQVLP VVMAGGGGTR LWPLSRAMHP KQFLVLQGNQ SLFQQATQRL ATLAADDIAV
AAPLIVGNEE HRFLVLDQLR ELKLPPATVL LEPVGRNTAP AMTLAALQAS ANGNDPVMVV
TAADHAYVNE AGFTRALQAA VRTAAGGAIV TLGILPTGPE TGYGYLRCTA TEGHDPSAAQ
RLAEFVEKPD LPTAQRYLAD GRYYWNSGIF VVRASVWLKA LRQFRPDIAS ATQTAWEGRS
TDAPFIRPDR AAFEAIPSES VDYAVMERCP ASPEFDIRMV PMDAGWSDLG AWDAVWEVSP
KDAAGNASHG DALMRDSRNT LVHATSRLVG VIGLDDVVVV ETPDAVLVTH RSRSQEVKQI
VGQLQRDGRT EHNLHRLVHR PWGWYDSIDA GGRFQVKRIM VKPGATLSLQ KHHHRAEHWI
VVRGTAEVTN GDQVLLLTEN QSTYIPLGQV HRLANPGKVP LEIIEVQSGS YLGEDDIVRF
EDTYGRVG
//
