ID   A0A257EJ14_9BURK        Unreviewed;       766 AA.
AC   A0A257EJ14;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:OYU13833.1};
GN   ORFNames=CFE38_01690 {ECO:0000313|EMBL:OYU13833.1};
OS   Comamonadaceae bacterium PBBC1.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae.
OX   NCBI_TaxID=2015580 {ECO:0000313|EMBL:OYU13833.1, ECO:0000313|Proteomes:UP000216161};
RN   [1] {ECO:0000313|EMBL:OYU13833.1, ECO:0000313|Proteomes:UP000216161}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBBC1 {ECO:0000313|EMBL:OYU13833.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU13833.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NKIP01000001; OYU13833.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257EJ14; -.
DR   Proteomes; UP000216161; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR041490; KstR2_TetR_C.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF17932; TetR_C_24; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00335}; Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          33..93
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        56..75
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   766 AA;  82213 MW;  054B7C780A3F8D7C CRC64;
     MPTIPAAKAS GRKATQSVDS PWSARLERDQ QHQTKKEAVL LSAARLFTRK GFQGTSLDDI
     AQSLGVTKPT LYYYIDNKEQ ILFECVEREL ALFRSGLQAL EAQGLLGRER LRAAMQLYAS
     VVTGDFGLCV SRVGEDPLSE ARRHELRKLK AQVDADFRAL IAQGMAEGWI VAGDPGVGAF
     SVVGAISGIG RWYRPEAHSD QSLQEAVSHC IEMLMRGVLS APHDTPSPHP AGDALNPAIR
     RESHFDHRIV RCYAERPATL AQMLGTAARQ FPQGAAMVCG DLRLSWHELH HAACKCAGGL
     AQRGIVAGDR VALHLGNGSE FVIATLACAW MGAVLVPVSS RARGVELEFA LNNAQAKALI
     CSAELADLQP VADNLPHLTC RIVTGSAARE GFESFGALMM APPLSTAYSG AEDDLAVLLY
     TSGTTGRPKG AMLSHLNIVH SVMHYAQLMG LSPQDRTAVA VPLSHVTGLV AQLYAMLYCG
     GCMVVMPQFK AADFIRLAAA EKITHTIMVP AMYNLCLLLP ELPSQDLSHW RIGAYGGASM
     PTATIDGLAD KLPGLVLMNA YGATETCSPA TIMPAGQTAA HRDSVGQVVP CGEICVVDEQ
     GNELPRGGVG EIWIAGPMVV SGYWQNPQAT ASEFTGGFWH SGDIGSMDAE GFVRILDRKK
     DVIIRGGYKV YCASVENILC EHPQVIEAAL VGVPCAVLGE RVHAFVCVRE LNDQTQASAL
     QAYGARLLAD YAVPETWTIG TEPLPRNLNG KIVKRELRQS LQAALI
//