ID A0A257EQ61_9PROT Unreviewed; 524 AA.
AC A0A257EQ61;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=CFE37_03150 {ECO:0000313|EMBL:OYU16048.1};
OS Alphaproteobacteria bacterium PA4.
OC Bacteria; Pseudomonadota; Alphaproteobacteria.
OX NCBI_TaxID=2015572 {ECO:0000313|EMBL:OYU16048.1, ECO:0000313|Proteomes:UP000215773};
RN [1] {ECO:0000313|EMBL:OYU16048.1, ECO:0000313|Proteomes:UP000215773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA4 {ECO:0000313|EMBL:OYU16048.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU16048.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NKIQ01000004; OYU16048.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257EQ61; -.
DR Proteomes; UP000215773; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OYU16048.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215773}.
FT DOMAIN 311..430
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 524 AA; 56901 MW; 96678988DF43C6CD CRC64;
MDAFAALLDA LLFAPGRNAK LRLIGAYLRT TPDPDRGWAL AALTGGLQLK AVQPSLIRAL
ISERVDPALF AYSYDFVGDL AETVSLLWPD PPVDAGPVSL SLDAIVQRLT GLSRAEAPAV
VASLLDGLTP QGRYALLKLA TGGLRVGVSA RLAKTALADA FGLDVEAVEE VWHGLSPPYR
PLFDWAEGRS PAPTANDVPV FRPFMLAHPL EAESVDLADY VAEWKWDGIR VQVTHVAGQT
RLFSRTGDDI TASFPDVAAA FRSHATLDGE LLVRGDAQKG EAASFNALQQ RLGRKAPPAK
LIGDYPAFVR LYDALTIAGA DLRALPWTER RARLAALMPQ LDASRFDLSA LVDAPDFAAL
AALRDAARDT AIEGLMLKRR DSPYVAGRRA GLWYKWKRSA LTIDCVLMYA QRGHGKRSGL
YSDYTFGCWS DAGELLPVGK AYSGFTDVEL AFLDKWIRGH TTGRFGPVRE VEKALVLEIA
FDSVHVSKRH KSGLAMRFPR VSRLRPDKPA HEADKIATLA GLIG
//
