ID   A0A257F0Z4_9RHOB        Unreviewed;       305 AA.
AC   A0A257F0Z4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=Glyoxylate reductase {ECO:0000313|EMBL:OYU19817.1};
GN   ORFNames=CFE34_03260 {ECO:0000313|EMBL:OYU19817.1};
OS   Rhodobacteraceae bacterium PARR1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae.
OX   NCBI_TaxID=2015578 {ECO:0000313|EMBL:OYU19817.1, ECO:0000313|Proteomes:UP000216502};
RN   [1] {ECO:0000313|EMBL:OYU19817.1, ECO:0000313|Proteomes:UP000216502}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PARR1 {ECO:0000313|EMBL:OYU19817.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU19817.1}.
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DR   EMBL; NKIT01000011; OYU19817.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257F0Z4; -.
DR   Proteomes; UP000216502; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR   PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216502}.
FT   DOMAIN          43..301
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT                   catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00389"
FT   DOMAIN          108..279
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   305 AA;  31522 MW;  B265D25D70F5CCDA CRC64;
     MTVILAFPAL AGMDYPALAE RALLRVVPDP DSIRGLDAAD RAAVRVLMTS ASRGCSVQMI
     ETLPSLGLVV SQGAGLDKID IPALKARGIR FRNIGETQTE DVADLAMALT QMLCRRLLLA
     DGFARSGAWV TARFDLGDSL YGMTMGIAGL SGRIGQAIAA RARASGMQIA GLNRASNAGL
     GHLHDGWQAL AAASDVLVMA VPGTDDLTGI IDGPVLAALG PKGRLVNVGR GNLVNMDALI
     HALETGAIAG AALDVIDSEP QVPARLAALQ NVILTPHIGA QTWGQRARAA QIAEAEILAY
     LAADG
//