ID   A0A257F1C6_9RHOB        Unreviewed;       832 AA.
AC   A0A257F1C6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:OYU19130.1};
GN   ORFNames=CFE34_06895 {ECO:0000313|EMBL:OYU19130.1};
OS   Rhodobacteraceae bacterium PARR1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae.
OX   NCBI_TaxID=2015578 {ECO:0000313|EMBL:OYU19130.1, ECO:0000313|Proteomes:UP000216502};
RN   [1] {ECO:0000313|EMBL:OYU19130.1, ECO:0000313|Proteomes:UP000216502}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PARR1 {ECO:0000313|EMBL:OYU19130.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU19130.1}.
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DR   EMBL; NKIT01000031; OYU19130.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257F1C6; -.
DR   Proteomes; UP000216502; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000216502}.
FT   DOMAIN          7..379
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          382..435
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          439..721
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          744..822
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   832 AA;  93213 MW;  027199D552C85C22 CRC64;
     MKTHVKALVV GGGAVGNGIA YHLAKAGWDT MLVERDELTA GSTWHAAGLL PLFNMSYATT
     HIHKYSVDFY KGLEAETGLN PGFYVVGNLR MAQRQERMDE YMLYSSVAET AGVYHEFLSP
     KEMKDRWPLL RTEDLVGALY HPQDGYINPA DVTQAMAKGA RQLGATIERK IQVNGYRWTG
     SEWIVSVTRM EDKGGNLQPT EEHYEIHAEH VVTATGNHAQ RTARLLGIKI PAIPVEHQYI
     VTEPDPALVE WRKTNPQHPV LRDADAKWYV REERGGWILG PYERNAPARF LYDVPAGFRA
     DLFPLDLERI ETEYMSMIHR LPSSETVGLK DDYNGPICYT PDGNPLVGPV PGLRNMWIAE
     GFSFGITAAG GTGHYLAQLM TEGEAEIDMA SLDPKRYGNW MTTEYAARKN EECYEHVFIL
     HHPDEEREAC RPLRTAPAYD RQKEMGAQFG QVNGWERPNY YGPKDAPASF DHDSRSFRRG
     AWWPHAEAEA KAVRNTVGII DASAFTKHLV RGPGATAFLD HFTCNKLPNV GRINLTYALT
     DHGTTRTEYT IVRLKEHEYY LISAGAWTAY DADFLIKAAE DWMANGGGYI DIHDITTQWG
     VYALAGPNAR ALLNDIVKDA NPDTVLSNKR FPWLSYRDIE LGMCPVRAVR VAYTGELGWE
     LHYPIEFGRY LWDLLWSVGE KHGLTGVGAR AQNWLRQEKS YRAFGNELGR DATPLEAALD
     RFVDLTKDFR GKAKMLETGI RSKCVTVLID GPADADPWGK EALLVDGVKV GRLTSGGYSV
     AFGKQIGMGY VPPHLAEVGT KLKVKMLRQE WDAVVVEDSP FDPSNARIRV DG
//