ID A0A257FLF4_9BURK Unreviewed; 817 AA.
AC A0A257FLF4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CFE41_14070 {ECO:0000313|EMBL:OYU26916.1};
OS Burkholderiales bacterium PBB2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=2015564 {ECO:0000313|EMBL:OYU26916.1, ECO:0000313|Proteomes:UP000215624};
RN [1] {ECO:0000313|EMBL:OYU26916.1, ECO:0000313|Proteomes:UP000215624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBB2 {ECO:0000313|EMBL:OYU26916.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU26916.1}.
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DR EMBL; NKIM01000020; OYU26916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257FLF4; -.
DR Proteomes; UP000215624; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OYU26916.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000215624};
KW Transferase {ECO:0000313|EMBL:OYU26916.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 330..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 440..657
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 685..804
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 734
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 817 AA; 88284 MW; 7FBFD6E020539532 CRC64;
MPEEVRGRGW RRWGPSCLAL PLALCVIVLA QGSGPLRPLD LALEDGLLRL TAQPLRVDEL
ALLDIDDDAL REMQPALGDW PYPRSVYALL LDYLQQVGAR RVVINLVLSG EREGDAELAQ
ALRTGPPSVL AAAGLQLEAA PSALPSEEQV VLKGLAWSAA PPGTPSLSWN ALMLPATPLL
REAPAALGRV GLVSSPLDSD GLLRRQPLWH RYQGQVLPAL PLAVLLQEQP ERLQALQRWP
LDAQGRVQLK LPSRLEGLPE LSWGRLMRAA LGQGEDPGLR ESLRGRTVFV GSSAYFADAV
STPQGRLSGS AFVATASALL ARGQVLAPAG WAWAAVLLLL AAVPGVLHAR SRAMQAQQRW
GLLLGSTALS LTLLLGLAVW LVQSQLLLPS LLGPLATLVL ALMLAGLAEQ RWQSLRHREL
RHAREVAEAA NQAKTEFLAH VSHEIRTPMN AVLGMAEILA RTELNAEQRR YVQVFQGAGQ
QLFALINDLL DNAKIEAGKL SLSPHAFHLG ELLRQQIDLQ QGRARERGLS LELCCTDEVE
AWVWGDAQRL AQVLANLLSN AIKFTRQGGV HLEVRRLEPG RWSLAVQDSG IGIPPAMQER
IFQPYTQADA SISREYGGTG LGLAISRSLV QMMGGQLSLS SVPGQGSRFE LNLPLPAQPT
PAPGELPPAP AASAPLAPRR LRPLRLLLCE DNEVNVLVIE AMLAPLGHAI EVAGDGEQAL
ACLQRGMYDL VLMDVQMPVL DGLEVTRRWR AIEAEMARPR LPILALTANA FARDVEQCLA
AGCDAHLSKP IGLQALEQAL ERWALPPEDA SPPSPQS
//
