ID   A0A257FZ89_9BURK        Unreviewed;       332 AA.
AC   A0A257FZ89;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase (Inverting) {ECO:0000313|EMBL:OYU31457.1};
GN   Name=pseB {ECO:0000313|EMBL:OYU31457.1};
GN   ORFNames=CFE39_08255 {ECO:0000313|EMBL:OYU31457.1};
OS   Comamonadaceae bacterium PBBC2.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae.
OX   NCBI_TaxID=2015581 {ECO:0000313|EMBL:OYU31457.1, ECO:0000313|Proteomes:UP000215754};
RN   [1] {ECO:0000313|EMBL:OYU31457.1, ECO:0000313|Proteomes:UP000215754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBBC2 {ECO:0000313|EMBL:OYU31457.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC         Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC         EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU31457.1}.
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DR   EMBL; NKIO01000024; OYU31457.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257FZ89; -.
DR   Proteomes; UP000215754; Unassembled WGS sequence.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   InterPro; IPR020025; PseB.
DR   NCBIfam; TIGR03589; PseB; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          7..278
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   332 AA;  37311 MW;  E44A3A854121C258 CRC64;
     MLREKTILVT GGTGSFGNTF VPMTLAKYNP KKIIIFSRDE MKQWDMAKKF QGDNRVRFFI
     GDVRDKERLY RALDGVDYVV HAAATKIVPT AEYNPFECIK TNVNGAMNLI DACIDKKVKG
     VVALSTDKAS SPINLYGATK LTSDKLFVAG NAYSGEHGSK FSVVRYGNVM GSRGSVIPFF
     MSIREKGVLP ITDERMTRFM ISLEQGVELV WHAFEDMVGG EIYVKKIPSM KVTDLARVVA
     PECKQEVVGI RPGEKLHEQM IGSEDSYYTF EYPEHFKILP TINDWGASPE RIKDGKKVPE
     GFIYSSDNNT EWMSDAELQA WIDSHRDKIG SI
//