ID   A0A257GJA7_9RHOB        Unreviewed;       434 AA.
AC   A0A257GJA7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Dihydropyrimidine dehydrogenase {ECO:0000313|EMBL:OYU37610.1};
GN   ORFNames=CFE33_20015 {ECO:0000313|EMBL:OYU37610.1};
OS   Pseudorhodobacter sp. PARRP1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Pseudorhodobacter.
OX   NCBI_TaxID=2015560 {ECO:0000313|EMBL:OYU37610.1, ECO:0000313|Proteomes:UP000215760};
RN   [1] {ECO:0000313|EMBL:OYU37610.1, ECO:0000313|Proteomes:UP000215760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PARRP1 {ECO:0000313|EMBL:OYU37610.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU37610.1}.
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DR   EMBL; NKIU01000015; OYU37610.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257GJA7; -.
DR   Proteomes; UP000215760; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43073; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   PANTHER; PTHR43073:SF2; DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215760}.
FT   DOMAIN          22..130
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          144..421
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   434 AA;  45448 MW;  DBF4A4F4F56628DA CRC64;
     MSNSPLTPGV VADRLPPAAY AENFSDVQPV LDRHEARVAA DRCYFCHDAP CMTACPTSID
     IPLFIRQIAT GTPDAAAKTI FAQNILGGMC ARVCPTEQLC EEVCVREVAE GKPVEIGRLQ
     RFATDTLMGK GVHPFTRAAA TGKRVAVVGA GPAGLACAHR LAMRGHDVVV FERRAKPGGL
     NEYGIATYKT PENFAAREVE WLLKIGGITV KTGVELGRDV TLDQLQADYD AVFLGIGLAG
     VNALRAVGED LAGVRNAVDF IAELRQSDKA QVAVGRDVVV IGGGMTAVDA AVQSKLLGAN
     SVTMVYRRGK DKMSASVYEQ DHATGAGVRI IYGAAPVKVL GSAAVEGVEF AYTHDGPNGL
     EMGETFTLKA DQVFKAIGQT LTAAPIAKDG AKLVKQQGKI WAGGDCAAGG EDLTVTAVAE
     GRDAAEAIHA SLMA
//